In WERA werden 11 kooperative Forschungsprojekte zur Rückgewinnung des wichtigen Rohstoffs Phosphor (P) aus Abwasser mit neuartigen natur- und ingenieurwissenschaftlichen Ansätzen bis zur technischen Umsetzung gemeinschaftlich und fachbereichsübergreifend bearbeitet. Es werden verschiedene Prozessbausteine wie die Synthese maßgeschneiderter Adsorbermaterialien und innovative Trennverfahren zur Phosphor-Rückgewinnung entwickelt, in Prozessketten kombiniert und an einer gemeinsam betriebenen Abwasser- und Recyclinganlage im Technikumsmaßstab erprobt. In WERA werden Methoden zur Prozessanalytik und -charakterisierung erweitert sowie chemisch-physikalische Zusammenhänge mit molekularen und thermodynamischen Simulationen untersucht. Der grundlagenbasierte Forschungsansatz in WERA erlaubt eine Übertragung der Erkenntnisse auf viele weitere Felder der Kreislaufwirtschaft.
Bei einer Promotion in WERA profitieren Sie von einer engen Zusammenarbeit von Doktorand/innen und einem interdisziplinären Professor/innen-Team, von einem breit angelegten Studienkonzept mit Summer Schools, Fachvorträgen von international renommierten Wissenschaftler/innen, themenspezifischen Ringvorlesungen und überfachlichen Workshops sowie von Angeboten zu Forschungsaufenthalten in internationalen Instituten. Eine Promotion in WERA ermöglicht Ihnen eine umfassende wissenschaftliche Ausbildung innerhalb von 4 Jahren zu einem/einer hochqualifizierten Experten/Expertin in den zukunftsträchtigen Bereichen der Ressourcenrückgewinnung und Umwelttechnik.
Es werden folgende Promotionsthemen angeboten, die auf der Webseite rptu.de/wera näher erläutert werden.
Im Fachgebiet Chemie:
A1: Synthese und Charakterisierung von mesoporösen Kieselgelen für die effiziente Abtrennung von P aus Abwasser Betreuer: Prof. Werner R. Thiel
A2: Synthese von mikroporösen Adsorbentien für die selektive Abtrennung von P aus Abwasser Betreuer: Prof. Wolfgang Kleist
A3: Entwicklung makroporöser polymerer Adsorbermaterialien für die Abtrennung von P aus Abwasser Betreuer: Prof. Stefan Kubik
B5: Synthese und Charakterisierung von Zinkkomplexen zur P-Detektion in Abwasser Betreuerin: Prof. Sabine Becker
Im Fachgebiet Physik:
B3: 57Fe-Mössbauer-Spektroskopie zum Verständnis von Fällungsreaktionen bei der P-Rückgewinnung aus Abwasser Betreuer: Prof. Volker Schünemann
Im Fachgebiet Verfahrenstechnik:
B1: Thermodynamische Modellierung der Kristallisation von P aus Abwasser, Betreuer: Jun.-Prof. Fabian Jirasek
B2: Molekulardynamiksimulation von Adsorptions- und Desorptionsprozessen für die P-Rückgewinnung Betreuer: Jun.-Prof. Simon Stephan
B4: Entwicklung einer dynamischen Extinktionsmethode zur Dispersitäts- und Kinetikanalyse von Fällungs- und Kristallisationsprozessen bei der P-Rückgewinnung Betreuer: Prof. Sergiy Antonyuk
C1: Synthese phosphatspezifischer magnetischer Partikel und ihre Charakterisierung bei einer Magnetseparation Betreuer: Prof. Roland Ulber
C2: Experimentelle Untersuchung und Modellierung eines Adsorptions-/ Desorptionsprozess zur Abtrennung von P aus Abwasser Betreuer: Prof. Erik von Harbou
Im Fachgebiet Abwassertechnik:
D1: Einfluss der Schlammmatrix und Betriebsbedingungen auf Fällungs- und Kristallisationsprozesse bei der P-Rückgewinnung Betreuerin: Prof. Heidrun Steinmetz
Bewerbung:
Bitte senden Sie bis zum 15.03.2024 vollständige Bewerbungsunterlagen:
direkt an die Betreuenden (siehe Kontaktdaten unter rptu.de/wera/team). Für generelle Fragen zum Graduiertenkolleg steht Ihnen der Sprecher des Graduiertenkollegs Prof. Sergiy Antonyuk (sergiy.antonyuk@mv.rptu.de) gerne zur Verfügung.
Voraussetzung für die Promotionsstelle ist ein überdurchschnittlicher Master-Abschluss (oder vergleichbar) in Chemie, Physik oder im Ingenieurwesen.
Zur RPTU Kaiserslautern-Landau:
Die Rheinland-Pfälzische Technische Universität Kaiserslautern-Landau (RPTU) ist mit über 20.000 Studierenden, mehr als 300 Professuren und rund 160 Studiengängen die Technische Universität des Landes Rheinland-Pfalz. Als Ort internationaler Spitzenforschung bietet sie exzellente Arbeitsbedingungen und Karrierechancen. Wer an der RPTU lernt, forscht oder arbeitet, erlebt ein weltoffenes Umfeld und gestaltet die Zukunft.
Das Graduiertenkolleg GRK 2908 wird durch die Deutsche Forschungsgemeinschaft (DFG) mit Mitteln von Bund und Ländern finanziert.
]]>RESEARCHER / PhD student (m/f/d)
full-time and preliminary limited until October 2025. An extension of another two years is foreseen. The position is funded by the Christian Doppler Laboratory for Blockchain Technologies for the Internet of Things (CDL-BOT) www.cdl-bot.at. The remuneration is in accordance with TV-L 13.
No.: 8424WE19
Your Tasks
Your Profile
Our Offer
For further information please contact Prof. Stefan Schulte (stefan.schulte@tuhh.de) and see
www.cdl-bot.at/en.
We particularly encourage women to apply. Due to their underrepresentation, they will be given priority in cases of equal suitability, qualifications, and professional performance.
Please send your complete application documents (cover letter, curriculum vitae in table form, proof of completed training and/or university degree, job references or certificates of employment, and latest thesis) via the online application system at https://stellenportal.tuhh.de/tzzf5
We look forward to receiving your online application by April 12th, 2024.
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Activities and responsibilities
The research group of Eva Wolf offers the following 2 PhD projects:
Many marine organisms time their reproduction according to the lunar cycle using an inner monthly calendar referred to as circalunar clock (Mat et al, 2023). Unfortunately, anthropogenic disturbances (e.g. nocturnal light pollution) are increasingly disturbing these moon-controlled reproduction cycles, imposing a threat to species survival and the marine ecosystem. Despite their high ecological relevance, the molecular bases of circalunar timing systems are still unknown.
The marine bristle worm Platynereis dumerilii (Pdu) is an emerging genetically tractable model system for mass-spawning marine animals. We recently showed that Pdu has a light-sensitive cryptochrome protein (L-Cry), that can discriminate between moonlight and sunlight and even between different moon phases, to enable the worm to synchronize its reproduction to the full moon phase (Pöhn, Krishnan et al, 2022). We found that L-Cry can form three distinct molecular states: 1. a dimeric, predominantly nuclear dark state with a fully oxidized light-sensing FAD cofactor, 2. a monomeric, predominantly cytosolic sunlight state with fully photoreduced FAD and 3. a half-reduced, predominantly nuclear moonlight state (Pöhn, Krishnan et al, 2022). Furthermore, we determined Cryo-EM structures of dark-state and light-activated L-Cry (Vu, Behrmann et al, 2023). To advance our molecular-mechanistic understanding of circalunar timing systems the prospective PhD students will investigate the molecular mechanisms underlying the differential responses of L-Cry to sunlight and moonlight, as well as L-Cry’s interactions with downstream ligands, using a combination of protein biochemical, spectroscopic, 3D-structural, molecular biology and cell-based approaches.
PhD Project 1: Molecular mechanisms underlying L-Cry’s responses to moonlight and sunlight
The aims of this project are to understand the molecular basis of the exceptionally high (moon)light sensitivity of L-Cry compared to its Drosophila CRY (dCRY) homolog (Zurl et al, 2022; Czarna et al, 2013; Berndt et al, 2007), to determine the molecular structure of the L-Cry moonlight state, to dissect conformational rearrangements, intermediate states and oligomeric state changes occurring during the transitions between the dark-, sunlight- and moonlight states of L-Cry, and to determine intensity thresholds separating moonlight- and sunlight state formation of L-Cry. These studies will elucidate molecular-mechanistic principles underlying moonlight receptor functions and help us predict the impact of nocturnal light pollution on L-Cry moonlight signaling.
The prospective PhD student will recombinantly express and purify L-Cry proteins (wildtype and mutants), analyse their light-response by time-resolved UV/VIS spectroscopy, analyse light-dependant changes of L-Cry’s oligomerisation state by SEC, native PAGE, MALS and native MS, determine L-Cry crystal structures and be involved in Cryo-EM studies of L-Cry.
If you are interested in this project, please select Wolf (light) as your group preference in the IPP application platform.
PhD Project 2: Molecular interactions and downstream signaling of L-Cry
To elucidate the molecular basis of circalunar oscillators, the PhD student will analyse L-Cry’s downstream signalling to the circalunar clock. To this end, she/he will search for new L-Cry interactors using pulldown/mass spectrometry (MS) under dark, sunlight and moonlight conditions, and mechanistically and functionally characterize their interactions with L-Cry in vitro and in vivo. Additionally, she/he will characterize L-Cry’s interactions with G3BP2 and YTHDF, which we previously identified as L-Cry ligands by pulldown/MS. YTHDF binds and decodes N6-methyladenosine (m6A) RNA modifications (Zaccara et al., 2019), whereas G3BP2 homologs are mostly involved in mRNA stability, RNA and protein transport as well as stress granule formation (Jin et al., 2022), indicating a link between L-Cry and RNA-dependant cellular signalling.
The prospective PhD student will recombinantly express and purify L-Cry proteins and L-Cry ligands, conduct pulldown/MS studies, test new ligands for direct binding to L-Cry in Y2H, SEC and pulldown experiments, and analyse the impact of the ligands on L-Cry’s light-response (time-resolved UV/VIS spectroscopy) and oligomerization (SEC, native PAGE, MALS, native MS). Stable L-Cry-ligand complexes will be subjected to structural studies using X-ray crystallography or Cryo-EM and their binding affinities will be determined by ITC, FP or SPR. Depending on the predicted roles of the L-Cry ligands, functional studies will be conducted, e.g. testing YTHDF binding to m6A methylated RNA.
If you are interested in this project, please select Wolf (int) as your group preference in the IPP application platform.
We encourage applications of highly motivated PhD candidates with a strong interest in structural biology, protein biochemistry, biophysics and structure-function relationship and a significant previous exposure to these research areas during their master education.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
We offer
For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
Activities and responsibilities
The research group of Sina Wittmann offers the following 2 PhD projects:
Transcription is one of the most fundamental processes of all cellular life. Precise regulation in time and space is needed for proper development and to adequately react to environmental changes. Misregulation, on the other hand, can lead to the establishment of serious diseases most notably cancer. The regulation of gene activation is achieved via a complex, multi-step process that starts by the recognition of DNA enhancer elements through gene-specific transcription factors which recruit downstream factors that help position RNA polymerase II correctly at the transcription start site for RNA synthesis to begin. Recently, it was discovered that transcription initiation sites constitute protein condensates with liquid-like properties. This exciting new finding has attracted much attention in the transcription community, as it can potentially explain cellular observations that were puzzling previously. This includes the simultaneous firing of different genes or the bursting behaviour of transcription. While we recently succeeded in reconstituting the formation of transcription factor condensates in vitro, little is known about their function or regulation inside cells. Furthermore, cellular condensates contain thousands of different proteins but how their composition is regulated is not fully understood.
Our newly developed reconstitution systems (see Morin et al. and Quail et al.) provide us with a tool to build initiation condensates in the test tube and to increase their complexity in a stepwise manner. To achieve this, we will use different biochemical methods including protein purification and characterization, reconstitution of condensates on DNA, and DNA binding assays. The insights obtained in this way will later on be tested in the complex environment of the cell to investigate the effect of condensation on gene expression more directly. Here, mammalian tissue culture will be utilized and a variety of genome-wide methods (e.g. ChIP-Seq, RNA-Seq, ATAC-Seq) will be performed. Different collaborations inside and outside Mainz will ensure the interdisciplinarity of our investigations.
We are a new research group that has started at the IMB in September 2023 and are looking for motivated PhD students to decipher how initiation condensates regulate gene expression.
PhD Project 1: Investigating the role of transcription factor condensation during chromatin opening
During de novo gene activation, chromatin has to transition from a closed to an open state that allows binding of the transcription machinery. This project will address important open questions about this transition: Can condensates form on nucleosomes and with which epigenetic modifications? Is transcription factor condensation important for histone modification? And finally, what is the role of condensation in chromatin opening (during gene activation)?
Here, we aim to reconstitute nucleosomes and recreate some of the early steps of chromatin opening in the test tube. Using the methods detailed above, the initial experiments will be performed in vitro using our reconstitution system to simplify the problem to its most relevant components. The biochemical results will be used to formulate testable hypotheses which we will investigate inside cells. This strategy will enable us to gain physiologically relevant insight into the interaction between transcription factor condensation and chromatin modification. My previous research focused on the famous Yamanaka pluripotency factor Klf4 which will be utilized here, too, together with other pioneer and non-pioneer transcription factors.
If you are interested in this project, please select Wittmann (TFC) as your group preference in the IPP application platform.
PhD Project 2: Formation and function of Ngn3 condensates during pancreas development
In the pancreas, different cell types develop from pancreas progenitor cells. One of them constitutes the hormone-producing endocrine beta-cells. Interestingly, the master transcription factor Neurogenin-3 (Ngn3) is both necessary and sufficient for the differentiation into endocrine cells. Using this system as a tool, we will be able to investigate the physiological role of condensation in pancreas development.
In this project, we will use the in vitro methods described above to test different Ngn3 variants that affect the protein’s condensation behaviour. After identifying interesting variants in this way, we will introduce them into pancreas progenitor cells for differentiation into beta cells. This approach will allow us to study the effect of Ngn3 condensation on cell differentiation. The entire project will be done in collaboration with a pancreas expert and will give insights into the biological role of transcription factor condensation.
If you are interested in this project, please select Wittmann (NGN) as your group preference in the IPP application platform.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
We offer
For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
Activities and responsibilities
The research group of Helle Ulrich offers the following 2 PhD projects:
We study regulatory mechanisms that govern cellular quality control. On the one hand, we are interested in DNA repair pathways and factors that ensure complete and accurate DNA replication in the face of DNA damage. On the other hand, we investigate the diverse signalling functions of the posttranslational protein modifiers, ubiquitin and SUMO. Most of our ongoing projects are therefore situated at the interface between protein regulation and genome maintenance. In our research, we combine methods in genetics, molecular and cell biology with protein biochemistry and advanced genomics tools, using both budding yeast and human cells as models.
PhD Project 1: Deciphering the ubiquitin code
The ubiquitin system plays a key role in determining the function and fate of proteins in virtually every biological pathway, including genome maintenance and gene expression. Most often, ubiquitin signalling is mediated by polyubiquitin chains attached to selected substrate proteins. Depending on the linkage between the individual ubiquitin moieties, such chains can adopt many distinct geometries and - by means of linkage-selective downstream effectors - convey distinct biological effects. In this manner, the ubiquitin system is implicated in a variety of pathways that protect us from diseases such as cancer, neurodegeneration and inflammation.
In our lab, we have developed tailor-made ubiquitylation enzymes that allow us to induce the polyubiquitylation of relevant cellular proteins in a controlled and linkage-selective manner. Here we will apply these tools to the investigation of ubiquitin signalling in selected biological contexts, including the processing of DNA polymerase-blocking lesions during DNA replication, the ubiquitin-dependent damage response pathway at DNA double-strand breaks, the contribution of ubiquitin and SUMO to biological condensates via phase separation and the protection from pathological protein aggregates. The project will involve biochemical as well as cell and molecular biological approaches and aims to eluciate the relevance of ubiquitin and SUMO signalling in cellular resilience mechanisms against ageing and disease.
If you are interested in this project, please select Ulrich (Ubi) as your group preference in the IPP application platform.
PhD Project 2: Mechanisms of replicative DNA damage bypass
One of the areas where ubiquitylation plays a major regulatory role is during genome replication, where DNA is particularly vulnerable to decay. Accordingly, the capacity of cells to deal with replication stress is a major factor protecting us from genome instability and cancer. Yet, the molecular details of how a replication fork travels across a damaged template are poorly understood. A multitude of factors, including the ubiquitylation of the replication factor PCNA, have been implicated in this process, but many questions remain: what determines whether a replisome stalls or simply moves across a lesion? How do replication forks reverse or collapse upon prolonged stalling? How do they recover? What is the influence of chromatin?
To address these questions, we are combining tools such as fluorescence microscopy, chromatin immunoprecipitation, next-generation sequencing, and quantitative mass spectrometry, to examine the influence of factors like chromatin structure, cell cycle, and replication timing on damage processing. We engage in collaborative research for real-time measurements of replication fork progression in live cells and develop methods for the genomewide mapping of lesions and replication intermediates. In this manner, we aim to determine the interdependencies and hierarchies of the factors involved in ubiquitin-dependent lesion bypass.
If you are interested in this project, please select Ulrich (DNA) as your group preference in the IPP application platform.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
We offer
For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
Doktorand*in (m/w/d)
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Dr. Carsten Deppermann
Juniorprofessor für Systemische Interaktionen der Hämostase
deppermann@uni-mainz.de
Activities and responsibilities
The research group of Johannes Mayer offers the following PhD project:
Within the epididymis, a balanced immune regulation is essential for sperm maturation and thus, the male fertility status. This immunotolerant environment needs to be maintained for immunogenic spermatozoa to mature, yet pro-inflammatory immune responses have to be readily established against invading pathogens that ascend through the urogenital tract. A dysbalanced immune regulation, i.e. caused by acute bacterial infections, frequently results in longterm fertility impairments. While the neighbouring testis is considered an immune-privileged organ, the cellular and molecular mechanisms that balance tolerant and immunogenic immune reactions in the epididymis still need to be defined.
Our previous studies revealed that the epididymis is densely populated by resident antigen presenting cells that are strategically positioned along the epididymal duct. Accordingly, proximal regions remain mostly unresponsive to bacterial infections in mice and men, while distal regions exhibit severe and persistent tissue-damaging immune responses that detrimentally affect the male fertility status. Our observations point to a unique role for Dendritic Cells (DC), which bridge the innate and adaptive immune system and balance tolerance at steady state with initiating immune response upon infection. Our preliminary data indicate that epididymal DC locally differentiate into distinct functional phenotypes and thus shape the local immune environments.
PhD Project: Identification of organ-specific and region-specific properties of conventional dendritic cells and their impact on the disease progression of acute bacterial epididymitis
Overall Aim: To understand the epididymis-specific properties of dendritic cells under physiological conditions and to assess changes in the course of acute bacterial epididymitis leading to a loss of the local immunotolerant environment.
Cutting-edge techniques, like scRNA-seq, CODEX and high dimensional flow cytometry, will be employed to comprehensively characterize the phenotypic and functional properties of region-specific epididymal murine DC at the steady state. Furthermore, the migratory properties and kinetics as well as the T cell activation status of specialized DC subsets will be assessed using photoconvertible transgenic mouse models and in vitro co-culture assays.
To mimic the clinical manifestations observed in epididymitis-patients, a well-established experimental mouse model of acute bacterial epididymitis will be established together with our close collaboration partners at the Justus-Liebig-Universität Gießen. Utilizing specific transgenic mouse strains targeted DC and monocyte depletions will allow us to assess the impact of DC and monocyte-derived cells on the regionalized immune response and the development of anti-sperm immunity and autoinflammatory responses.
If you are interested in this project, please select Mayer (EPI) as your group preference in the IPP application platform.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
We offer
For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
Activities and responsibilities
The research group of Susans Schweiger offers the following PhD project:
Substantial differences between male and female have been observed in susceptibility of neurodevelopmental diseases. The second X-chromosome in female could play an important role in the molecular mechanisms underlying female resilience.
In comparison to males with one X and a Y-Chromosome, females with two X-chromosomes have a higher gene dosage. For dosage compensation one of the two X-chromosomes in female cells is randomly inactivated through epigenetic modification. However, several genes on the inactive X-chromosome escape inactivation and are expressed from both X-chromosomes. Such bi-allelic expression can lead to a substantial female expression bias and, through gene-gene interactions can significantly influence gene expression in female cells.
PhD Project: Implications of selective escape from X-inactivation in neurodevelopmental disorders
We hypothesize that such expression biases underly the sex differences in disease susceptibility during neurodevelopment. To strengthen this hypothesis, we are analysing bi-allelic expression of X-chromosomal genes in differentiating neurons and non-neuronal cells in the brain including astrocytes, microglia and immune cells that invade the developing brain. We are also looking at the mechanisms underlying tissue-dependent escape and are studying the effects of expression biases of selected genes on cell function and disease susceptibility. We are working in human iPSC generated models and in mice.
If you are interested in this project, please select Schweiger (Xinact) as your group preference in the IPP application platform.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
We offer
For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
Activities and responsibilities
The research group of Daniela Kramer offers the following PhD project:
Lupus erythematosus (LE) is a complex autoimmune disease. Once fully established, response to immunosuppressive therapy is unsatisfactory, disease is lifelong and cumulative damage and glucocorticoid toxicity occur. A key determinant of short and long-term outcomes is initial diagnosis and treatment. In other autoimmune diseases such as rheumatoid and psoriatic arthritis, early intervention has been shown to induce disease remission, prevent organ damage, and even prevent disease onset. Understanding early events in the LE disease process would facilitate early diagnosis and reveal targets for early intervention, changing the current paradigm from ‘long-term management of chronic inflammation’ to ‘prevention’.
SLE is diagnosed by the presence of antinuclear antibody (ANA) and a combination of other clinical symptoms (e.g. dermatitis and arthritis). ANA can be detected in serum up to 10 years before clinical features develop and is much more common than SLE, affecting 5-10% of healthy adults. Individuals with ANA therefore constitute an At-Risk population of whom a minority progress to SLE. There is also lack of knowledge regarding the regulatory mechanisms at play which prevent development of SLE in most ANApos individuals.
Thus, the most important current gaps in knowledge affecting patients’ outcome are
PhD Project: From altered skin signature to Lupus: understanding early events in cutaneous Lupus inflammation with regard to disease or health outcome
This project will address these knowledge gaps. We have previous experience with a unique preclinical At-Risk cohort (people referred with positive ANA, musculoskeletal symptoms but not initially diagnosed with SLE) that has already revealed novel insights into mechanism of initiation. Based on these findings, we aim to focus in this project on the early molecular autoimmune and regulatory events in the skin.
Overall Aim: To understand the molecular events within the skin compartment that lead to breakdown OR maintenance of tolerogenic responses in initiation of LE.
This project will focus on establishment and regulation of the cutaneous type I interferon (IFN) response. In close collaboration with a specialised clinic for “early” Lupus we will investigate blood and skin immunological parameters which may support development into Lupus disease OR protection from developing Lupus.
Methods will include cell culture including with patient derived skin and blood cells, flow cytometry including with skin and blood derived cells, scRNAseq, spatial transcriptomics, proteomics (mass spectrometry, multiplex ELISA techniques). Working with patient derived samples and thus some flexibility regarding timing of the planned experiments will be necessary.
If you are interested in this project, please select Kramer as your group preference in the IPP application platform.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
We offer
For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
Activities and responsibilities
The research group of Stamatis Papathanasiou offers the following PhD project:
Proper division of the genomic material is fundamental for cell homeostasis. Although cells have developed a plethora of mechanisms to ensure error-free division, mistakes during mitosis are common in normal physiology and a hallmark in disease. Such mistakes give birth to dysbalanced, aneuploid genomes. A prominent manifestation of mitotic errors is the generation of abnormal nuclear structures, such as micronuclei and chromosome bridges, common features of nuclear atypia in cancer with major physiological significance. Micronuclei are miniature, additional nuclei that form when a chromosome lags during mitosis and then recruits its own nuclear envelope. These structures accumulate massive DNA damage and can lead to severe rearrangements by mechanisms that are now starting to be understood. Yet, we do not fully understand the effects of dysbalanced genomes on cellular function and how these abnormalities contribute to disease initiation and progression.
We recently discovered a new phenomenon of heritable chromatin and transcriptional defects mediated by micronuclei. These alterations are inherited after the micronuclei reincorporate into the normal nuclear environment of daughter cells and are strongly associated with long-lived DNA damage. This work showed that chromosomal instability is inherently coupled to variation in gene expression, which may impact tumor evolution and provided significant insight into the elusive mechanisms leading to non-genetic, cell-to-cell epigenetic variability observed in pathophysiology.
PhD Project: Chromatin state dysregulation due to abnormal mitosis
Under what exact circumstances cell division errors can give birth to massive DNA lesions and other chromatin alterations, their inheritance in the progeny and their functional significance remain a mystery. The potential involvement of additional mitosis-mediated mechanisms - other than micronucleation - that initiate cascades of non-genetic alterations is also a black box.
We are excited to welcome a PhD candidate to attack these questions. We will combine cutting edge techniques, such as genome engineering and single-cell genomics together with advanced systems to track mis-segregated chromosomes by live-cell imaging over multiple generations. In parallel we will build upon our new experimental and computational framework that links phenotype to function at the single-cell level (named “Look-Seq2”). We will identify potential sources of inherited abnormal nuclear structures, investigate their DNA damage/repair dynamics and determine the immediate and long-term effects on these nuclear bodies’ chromatin state.
If you are interested in this project, please select Papathanasiou as your group preference in the IPP application platform.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
We offer
For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
Activities and responsibilities
The research group of Björn Clausen offers the following PhD project:
The oral mucosa represents a barrier tissue to the environment where the balance of immunity and tolerance is vital, as it is constantly exposed to pathogens and harmless foreign antigens, including commensals. A breakdown of this balance leads to dysbiosis resulting in periodontitis, an infection-induced inflammatory disease characterized by irreversible destruction of the tooth-supporting tissues including loss of the underlying bone. Moreover, it is considered a risk factor for life-threatening conditions such as cardiovascular disease. Dendritic cells (DC), including Langerhans cells (LC), have the unique capacity to promote both tolerogenic and inflammatory immune responses. Hence, in order to design effective therapeutic strategies to treat periodontitis and reduce the risk of developing comorbidities, it is essential to understand how DC in the oral mucosa maintain immune homeostasis.
PhD Project: E-cadherin and β-catenin signaling in dendritic cells for the maintenance of immune homeostasis in the oral mucosa
One pathway that plays a crucial role in DC homeostasis and tolerance induction is E-cadherin/β-catenin signaling. The cell adhesion molecule E-cadherin is only expressed by LC and we recently showed that it is involved in the 2-step process of their differentiation in the oral mucosa. Notably, to what extent E-cadherin/β-catenin signaling regulates LC/DC homeostasis and function in the oral mucosa is not known. In pilot experiments, we analyzed the oral mucosa of transgenic mice lacking E-cadherin in CD11c+ cells (CD11c-EcadDEL) and observed an altered LC subset distribution and a dramatically changed morphology with more rounded cell bodies and fewer dendrites compared to controls. In the proposed project a detailed in vivo and in vitro analysis of CD11c-EcadDEL and β-catenin deficient (CD11c-βcatDEL) mice will be performed. First, we will assess LC and DC homeostasis, activation and migration in the different oral tissues by high-dimensional flow cytometry as well as the impact of CD11c-specific E-cadherin or β-catenin deletion on other immune cell populations. Moreover, we detected oral dysbiosis in our CD11c-EcadDEL mice and therefore, a detailed taxonomic microbiota analysis will be performed in this project. Since persistent microbial dysbiosis results in inflammation and subsequently alveolar bone loss, we will analyze the oral tissues of CD11c-EcadDEL and CD11c-βcatDEL mice for T cell infiltration and inflammatory cytokines. Bone loss will be monitored by micro computed tomography (µCT) scans. Finally, in different mouse models of periodontitis (P. gingivalis- and ligature-induced periodontal disease) we will interrogate the impact of E-cadherin/β-catenin signaling on LC/DC during infection and inflammation. Applying single-cell RNA sequencing the molecular pathways affected by E-cadherin/ β-catenin signals in oral mucosal LC/DC will be deciphered. Our expected findings may thus have important implications for designing improved LC/DC-based strategies for the treatment of periodontal disease.
If you are interested in this project, please select Clausen as your group preference in the IPP application platform.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
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For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
Activities and responsibilities
The research group of Wolfram Ruf offers the following PhD project:
Throughout life, a finely regulated balance between quiescence and activation allows the hematopoietic stem cell (HSC) to continuously replenish all mature blood cells in homeostasis and in response to challenges. However, in aging HSCs become dysfunctional and show differentiation imbalances toward an increased production of myeloid cells at the expense of the adaptive immune lymphocytes. This has been associated with an increased risk of age-related conditions including cardiovascular complications, impaired immune responses, and myeloid premalignancies. The changes in aging HSCs result not only from accumulation of cell intrinsic insults but also from cell extrinsic effects. Within the bone marrow (BM), HSCs interact with several cellular and matrix (growth factors, extracellular vesicles) components which are crucial in the regulation and maintenance of HSC fate. While it has been shown that aged HSC can be partially rejuvenated once exposed to a young BM microenvironment, it is not clear which environmental cues contribute to the aging of the hematopoietic system. Proteases of the coagulation system have been implicated in the regulation of HSC fate (extravascular coagulation signaling) in homeostatic condition as well as in aging mouse models. Characterization of these interaction could provide new approaches to counteract or delay age-associated exhaustion of HSC.
PhD Project: Impact of intercellular interaction within the bone marrow microenvironment on hematopoiesis during aging
The aim of the project is to determine the contribution of interactions within the BM microenvironment (e.g. mesenchymal stromal cells and endothelial cells) to disrupted HSC function and unbalanced hematopoiesis in aging. Ultimately, the long-term goal will be to identify targets for the development of rejuvenation strategies. The work of the PhD candidate will include the interrogation of single cell sequencing datasets (established in the host lab) of young and old hematopoietic progenitors in different mouse models with an accelerated aging phenotype. This will lead to the identification followed by validation, via application of state-of-the-art BM imaging and functional assays, of possible regulators of age-associated reprogramming. Furthermore, different mouse models with accelerated senescence in stromal cells will be employed to address the impact of the BM microenvironment on aging of HSC. Characterization of the senescent associated secretory phenotype BM environment (e.g. of extracellular vesicles) may also be required to identify underlying molecular mechanisms for altered interaction that affects HSC output in aging.
A sound knowledge in molecular and cell biology and/or protein chemistry and an interest in working with animal models are expected for successful candidates. The candidate should have an interest in systems biology approaches and develop skills to apply bioinformatics on newly generated and available omics data sets for further validation in in vivo models of aging. This will be an interactive project involving different research groups which provide a variety of learning opportunities and interdisciplinary approaches.
If you are interested in this project, please select Ruf as your group preference in the IPP application platform.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
We offer
For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
Activities and responsibilities
The research group of René Ketting offers the following PhD project:
Gene regulation by small non-coding RNAs is a deeply conserved mode of gene control. It is used in developmental control of gene expression, but also in the protection of the genome against mobile genetic elements (i.e. transposons). The small RNA molecules function as sequence specific guides for proteins of the Argonaute family, which can repress translation, induce endonucleolytic cleavage or induce heterochromatin upon recognition of transcripts with sequence homology to the small RNA. Hence, the small RNA co-factors are essential players in these pathways as they fully determine the specificity. However, a lot still remains to be discovered about how such small RNAs are made, in particular in the context of genome defense against transposons. Understanding these steps better will increase our understanding of how our genomes discriminate ‘self’ from ‘non-self’, a non-trivial exercise! In addition, past work has shown that the dissection of such pathways has yielded great insights also in the understanding of more basic RNA biology. We are addressing these questions using two model organisms: the nematode C. elegans and the zebrafish. We are looking for people with a strong natural curiosity, perseverance and a high intrinsic motivation. Specific knowledge of the applied techniques is not essential, but a strong basis in molecular biology is required. We offer a highly interactive, stimulating and flexible research environment, with ample opportunities for personal development.
PhD Project: Biogenesis and regulation of small RNAs
Which small RNAs are made is of great importance, as the specificity of these pathways depends on it. Recently, we identified a novel nuclease that is a key factor in the generation of a specific type of small RNAs (named piRNAs), and we are further pursuing studies to understand how these piRNAs are made, starting from their transcription, all the way to their binding by a specific member of the Argonaute protein family (the Piwi protein). These are important research questions, as they relate to a much broader problem: how are certain RNA molecules destined to become used as protein-coding messengers, others to be degraded fast, and yet others to be used as (precursors for) non-coding RNAs, such as piRNAs. Resolving these questions will require a much better understanding of different modes of transcription initiation, elongation and termination, and RNA stabilization and de-stabilization, and RNA transport through the nucleus and the rest of the cell. Our recent, unpublished work has made intriguing entries into various of these aspects: we have identified a complex that stabilizes piRNA precursors, and are now studying how this connects to their transcription; we have generated mutants in a nuclear export factor that likely plays a role in piRNA precursor export and we have identified a novel locus that can serve as a source of piRNA precursor transcription.
Depending on expertise and interest, you can join us in studying these aspects, using C. elegans or the zebrafish as model system. The aims of the project can relate to understanding how ‘non-standard’ transcripts can be stabilized for further use, how the nuclear export of such transcripts is taking place, piRNA precursors actually look like, how the loading of small RNAs into an Argonaute protein takes place or how these processes can be regulated by post-translational modifications. Techniques that will be used in this project include microscopy, genetics, CRISPR-Cas genome editing, RNA interference, RNAseq, analysis of sequencing data and protein purification.
If you are interested in this project, please select Ketting as your group preference in the IPP application platform.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
We offer
For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
Activities and responsibilities
The research group of Johannes Mayer offers the following PhD project:
Type 2 immune signals control a variety of innate and non-immune mechanisms linked to parasite expulsion and toxin inactivation. While highly relevant in the context of evolution, uncontrolled type 2 immune activation has been linked with negative outcomes, such as allergies and immune suppression in many industrialized countries. Local type 2 immune cell circuits play a major role in tissue-specific disease progression and play a prominent role in barrier tissues.
These type 2 immune circuits are controlled by alarmin or neuropeptide signalling and alarmin responses have a strong activating effect on Innate Lymphoid cells (ILC), Dendritic Cells (DC) and T cells. Our preliminary work however suggests neuro-immune signalling plays an important role in defining the homeostatic type 2 signature prominent in healthy skin, while alarmin signalling drives detrimental type 2 immunity.
PhD Project: Defining dermal Neuro-Immune Interactions that drive beneficial and detrimental type 2 immunity
Overall Aim: To understand the properties of dermal Neuro-Immune Networks in the context of homeostatic type 2 immune signalling and wound healing vs. neurodermitis associated inflammation.
Cutting-edge techniques, like scRNA-seq, 3D imaging and high dimensional flow cytometry, will be employed to comprehensively characterize the phenotypic and functional properties of dermal Neuro-Immune Networks in the murine skin. Interactions will be validated in vitro and molecular signalling cascades assessed in important immune cell populations, such as ILC, DC and T cells.
These interactions will be monitored in the context of neurodermitis associated inflammation and transgenic mouse strains will be used to determine the importance of neuropeptide expression and signalling in the context of disease.
If you are interested in this project, please select Mayer (Neuro) as your group preference in the IPP application platform.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
We offer
For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
Activities and responsibilities
The research group of Katharina Papsdorf offers the following PhD project:
Aging is characterized by the gradual decline of tissue function. However, age progression can be slowed by interventions such as diet. One key component of the diet are lipids, which serve as energy reservoirs, and are also essential to cellular homeostasis as they constitute the building blocks of membranes. In the context of aging, specific lipids are potent modulators of lifespan. For example, monounsaturated fatty acids correlate with human longevity and extend lifespan in C. elegans. However, despite their importance for cellular and organismal homeostasis it remains largely unknown how lipids drive cellular changes underlying aging and if those can be leveraged to promote longevity. Our overarching goal for is to understand how organelles involved in lipid homeostasis influence lifespan.
PhD Project: Identification of how lipid droplets impact tissue homeostasis during aging and longevity
The major lipid reservoirs in cells are lipid droplets. These conserved cellular organelles are key for lipid metabolism as they are specialized in storing lipids and they are differentially regulated during aging and disease. We recently discovered the beneficial effect of lipid droplets for longevity especially in the context of monounsaturated fatty acids. However, which mechanism is supported by lipid droplets during longevity remains largely unclear. One exciting possibility is that lipid droplets are beneficial when they accumulate in lipid storage tissues by providing energy during the geriatric stages of life and by sequestering toxic lipids that could damage membranes. To understand how lipid droplets modulate longevity in vivo, the PhD student will use C. elegans lifespan studies in combination with tissue-specific manipulations (via RNAi), metabolomics mass spectrometry, and cell biology including fluorescence microscopy. The project builds on preexisting mutants and protocols to manipulate cellular lipid content as well as on lifespan assays that we are currently executing. The PhD student is expected to perform bioinformatic analysis of gene expression and mass spectrometry datasets supported by IMB’s core facilities and preexisting expertise of the group. Training on all aspects of the project will be provided to support the PhD student and no specific expertise is required other than a strong background in cell biology (molecular biology, biochemistry or related). A high motivation for fundamental biology and excellent teamworking skills are required.
If you are interested in this project, please select Papsdorf as your group preference in the IPP application platform.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
We offer
For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
Activities and responsibilities
The research group of Andreas Wachter offers the following PhD project:
Alternative splicing (AS) massively increases transcriptome complexity in higher eukaryotes, with critical implications in developmental processes and stress responses. Studying AS events in model systems revealed the existence of diverse regulatory principles, however, the mechanisms by which rapid and coordinated changes in the AS output can be achieved are still poorly understood. The Wachter group and others have previously shown that early seedling photomorphogenesis is accompanied and driven by AS changes. Furthermore, several splicing regulatory proteins involved in light-dependent AS and seedling development have been identified. In our ongoing research, we examine the molecular mechanisms and signaling pathways underlying rapid re-programming of the transcriptome via AS to steer seedling development in a light-dependent manner.
PhD Project: Light-dependent localization and interactions of RS splicing regulators in plant development
Illumination of etiolated seedlings triggers an extensive developmental re-programming from skoto- to photomorphogenesis, involving massive changes on the level of gene expression, metabolism, and growth. In our previous studies, we have identified light-triggered AS in etiolated Arabidopsis thaliana seedlings as a critical component of photomorphogenesis (Hartmann et al., 2016). Moreover, we have demonstrated an important role of the central energy sensor kinases SnRK1 and TOR in the upstream signaling (Saile et al., 2023). Transducing light signals into an AS response involves RS splicing regulators, which are differentially phosphorylated upon illumination of dark-grown seedlings. Altered photomorphogenesis of A. thaliana mutants with elevated or diminished RS protein levels corroborated their functional relevance in this process. Interestingly, RS proteins mainly localize in the nucleoplasm of etiolated seedlings, while light exposure can trigger their altered sub-nuclear distribution in speckles. Studying the underlying mechanisms and functional consequences of these sub-cellular localization patterns are the key goals of this PhD project. In the first experimental strategy, reporter lines for determining the dynamic localization patterns of RS proteins in a light- and tissue-specific manner will be established and analyzed. These experiments will also address the underlying mechanisms, such as the impact of RS phosphorylation and other protein features, which are studied in vitro by our group as part of the SFB 1551 on biomolecular condensates. The second line of research will identify in vivo interactors of RS proteins. Here, interacting proteins will be captured mainly using proximity labelling, while RNA targets can be searched for using TRIBE, an editing-based detection system recently optimized in our group (Loeser et al., accepted).
If you are interested in this project, please select Wachter as your group preference in the IPP application platform.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
We offer
For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
Activities and responsibilities
The research group of Roopesh Anand offers the following PhD project:
The genomic integrity is extremely important for the normal cellular functions. However, cells are routinely challenged by various DNA damaging events leading to the formation of different DNA lesions. In addition to environmental (external) factors like UV, X-rays, ionizing radiations etc., cellular processes like hydrolysis, oxidation, alkylation, impediment to replication fork etc., can also damage DNA endogenously. Cells have evolved multiple DNA repair pathways to deal with these DNA lesions. DNA double strand breaks are one of the most complex and thus deleterious DNA lesions to repair. The major pathways used by cells to repair DSBs are non-homologous end-joining (NHEJ) and homologous recombination (HR). Usually, HR is considered “error-free” pathway as the broken DNA duplex finds and invades the sister chromatid (or homologous chromosome) to use it as template to copy and recover the broken DNA sequence. In comparison to HR, NHEJ is “error-prone” as it frequently requires processing (e.g., deletion) of broken ends before ligating them together. Importantly, the defective DSB repair can lead to cancer, immunological deficiencies, accelerated ageing and severe developmental abnormalities.
Besides HR and NHEJ, cells can also use other additional “alternative” DSB repair pathways in certain specific situations. Cancer cells experience DNA damaging stress due to faster replication rate and thus they often hijack alternative repair pathways to overcome such stress. Break-induced replication (BIR) is one of the homology-directed alternative DSB repair pathway, which itself is highly mutagenic. BIR usually occurs at the single-ended DSBs where the second end is missing to carry out the more “accurate” HR. The basic mechanism of BIR underlies other deleterious processes/events like MiDAS (mitotic DNA synthesis), microhomology-mediated BIR (MMBIR) and certain form of chromothripsis. BIR is also postulated to be responsible for generating gross chromosomal rearrangement (GCR) found in neurological and neurodevelopmental disorders known as Pelizaeus-Mezbacher disease (PMD) and MECP2 duplication syndrome respectively. Most importantly, a form of BIR, known as ALT (alternative lengthening of telomers), is used by cancer cells to extend and thus maintain the critical length of telomers to avoid cell death. Around 10-15% of all cancers use ALT for telomere extensions to achieve unrestricted proliferation of cancer cells.
PhD Project: Investigating break-induced replication repair by in vitro reconstitution system
Genetic instability (GIN), with high mutation rates and chromosomal rearrangement in pre-cancerous cells, enables these cells to achieve transformation and unrestricted growth. The error-prone repair of one-sided DSB via BIR is postulated to be one of the underlying causes of GIN. As explained above, BIR is highly mutagenic and exhibits ~2800-fold elevated mutation rates compared to normal DNA replication. This is largely due to its unusual mode of conservative replication of newly synthesized DNA, lack of the S-phase processive replisome and mismatch correction, and longer persistence of ssDNA. While yeast genetics have uncovered many features of BIR, its molecular mechanism and the details of mammalian BIR is poorly understood. The latter is especially difficult to study due to impressively large heterogeneity and stochastic nature of the BIR/ALT found in mammalian cells. To circumvent this issue, we aim to address this outstanding problem in our research group by reconstituting BIR in vitro for both yeast and mammalian system using bulk biochemistry and single-molecule imaging (SMI) techniques, supported by cell biology. This PhD project will involve characterizing the molecular mechanism of BIR in unprecedented details using purified proteins, ensemble biochemistry and SMI techniques such as optical dual tweezer system (C-trap, Lumicks) and TIRF (total internal reflection microscopy)-based platforms. Later, the in vitro findings will be supported and validated by cell biology-based assays. The establishment of BIR at single-molecule level will be transformative for the understanding of BIR mechanism and its role in cancer development
We are looking for motivated PhD student with strong interest in the mechanism of DNA damage response, genomic instability, and cancer development. Ideally, the interested candidate will have some prior experience of molecular biology for cloning, protein expression and purification, and biochemical assays. However, lack of experience in these techniques should not stop you from applying if you are strongly interested in learning the requisite skills. You bring your enthusiasm and determination; we will do the rest.
If you are interested in this project, please select Anand as your group preference in the IPP application platform.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
We offer
For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
Activities and responsibilities
The research group of Christof Niehrs offers the following PhD project:
Poly-ADP-ribosylation (PARylation) is a widespread post-translational modification of proteins. In mammalian cells, PARylation is regarded as protein-specific modification. However, we recently discovered that DNA in mammalian cells is PARylated. in mouse embryonic stem cells, mouse heart and muscle, brain, thymus, liver, placenta, and human liver. Furthermore, the modification is reversible by PAR glycohydrolases. We also discovered that DNA PARylation occurs on N1-deoxyadenosine, both in vitro and in vivo. Thus, N1-adenosine PARylation is a novel, reversible DNA modification in mammals (Musheev et al., 2022). This discovery raises many questions regarding the physiological role of DNA PARylation.
PhD Project: Role of DNA PARylation in Epigenetic Gene Regulation
In this project, you will examine the role DNA PARylation in mouse embryonic stem cells (mESCs). You will generate and characterize PARylation-defective mutant mESCs by a variety of assays, including standard molecular biology, CRISPR Cas9 gene editing, confocal microscopy as well as Next-Generation-Sequencing. You will learn to analyze these Big Data by bioinformatic analysis. Thereby you will analyze epigenetic profiles in mESCs, to understand the molecular networks involved. You will also characterize PARylation-defective PARP enzymes involving recombinant protein expression and in vitro DNA Parylation.
You will work in a team of cell and molecular biologists and bioinformaticians. The successful candidate will have a strong background in Molecular-or Cell Biology.
If you are interested in this project, please select Niehrs as your group preference in the IPP application platform.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
We offer
For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
Activities and responsibilities
The research group of Anton Khmelinskii offers the following PhD project:
Protein quality control systems maintain a functional proteome through detection and removal of abnormal proteins. Due to inherent inefficiencies of cellular processes, formation of abnormal proteins is a constitutive problem. Moreover, proteome homeostasis can be challenged by stress conditions, disease mutations and declines with aging. Thus, understanding how cells deal with abnormal proteins is not only important from the point of view of basic research but will also contribute to understanding the molecular events of the aging process.
Various types of abnormal proteins are recognized by the ubiquitin-proteasome system via short motifs called degrons and marked for proteasomal degradation. A wide variety of degrons can be found at protein termini across all eukaryotes. We have recently identified a pathway that specifically targets degrons located at protein C-termini. This C-degron pathway has unexpectedly broad specificity, recognizing a variety of C-degron motifs, but its functions remain largely unknown (Kong et al. 2023).
PhD Project: Quality control of mislocalized proteins
In this project, we will dissect functions of C-degron pathways through a combination of high-throughput screening, molecular biology, genetics and biochemistry. We will take advantage of powerful yeast genetics and high-throughput mutagenesis approaches to identify endogenous substrates of C-degron pathways and understand their functions in protein quality control and aging.
We are looking for a highly motivated individual with a degree in Molecular Biology, Biochemistry, Biotechnology or related fields. The successful candidate will join an enthusiastic team and combine genetic screening approaches with deep mutational scanning, proteomics, biochemistry and molecular biology techniques to uncover substrates and functions of C-degron pathways. Excellent core facilities in the institute will provide the necessary support with mass spectrometry, sequencing and flow cytometry requirements of the project.
If you are interested in this project, please select Khmelinskii as your group preference in the IPP application platform.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
We offer
For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
Activities and responsibilities
The research group of Claudia Keller Valsecchi offers the following PhD project:
Diploid organisms contain a maternal and a paternal genome complement. A characteristic feature of a diploid karyotype is that the chromosomes and genes are present in correct proportion with respect to each other, which is referred to as gene dosage. Having two sets of chromosomes provides robustness and allows developmental progression when genetic perturbations occur in heterozygosity. However, a subset of genes are highly dosage sensitive: either an increase or decrease in copy number can reduce fitness and ultimately lead to organismal death.
Sex chromosomes are an interesting exception, as female humans contain two X chromosomes, while males have only one X and one Y chromosome. To account for these differences in copy number, the production of X-linked genes is corrected by dosage compensation. This epigenetic mechanism orchestrated by chromatin-modifying activities and noncoding RNAs ensures a collective finetuning of hundreds of genes on the X chromosome.
Sex differences are highly relevant in mosquitos, as only female mosquitoes feed on blood and are thereby able to transmit infectious diseases. Understanding sex differences and sex chromosomes has major implications for opening up new ways to control e.g. malaria by controlling its vector. However, our current knowledge of the molecular mechanisms regulating sex chromosomes and dosage compensation is utterly limited to only three model organisms (fruit flies, nematodes, and mice). Excitingly, our group has recently discovered the first component of the X chromosome dosage compensation pathway in the malaria mosquito Anopheles gambiae (Kalita et al., Nature, 2023).
PhD project: Characterization of a novel dosage compensation mechanism
The PhD student will work on the molecular mechanisms underlying this entirely new form of gene dosage control. We will use next-generation sequencing and mass spectrometry to characterize the downstream effectors responsible for this compensatory mechanism. We will then explore the cellular and genomic regulation of these pathways using molecular biology, screening and microscopy approaches.
We are looking for a PhD student with a strong interest in mechanisms of gene regulation, genomics, evolutionary biology and/or biochemistry. Our ideal candidate would like to combine wet lab and computational approaches. If you are a team player and have a high level of motivation and enthusiasm for science, you are the right person for our group.
If you are interested in this project, please select Keller Valsecchi as your group preference in the IPP application platform.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
We offer
For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
Activities and responsibilities
The research group of Sandra Schick offers the following PhD project:
BAF chromatin remodellers are polymorphic complexes, subdivided into three major subtypes (cBAF, PBAF, GBAF) that regulate the accessibility of chromatin by sliding or ejecting nucleosomes. BAF complexes are primarily known for their role in gene regulation. However, there is increasing evidence that BAF complexes are also actively implicated in genome stability processes, especially those that involve DNA double-strand breaks (DSBs), in ways that are also likely independent from their chromatin remodelling functions. However, we know very little about the putative differential roles of individual BAF subunits and BAF subtypes in the protection and repair of DSBs, where in the genome DSBs occur upon BAF perturbation and how genome instabilities caused by BAF perturbations are linked to cancerogenesis. More than 20% of all cancers have a mutation in a gene encoding a BAF subunit.
PhD Project: Systematic investigation of the role of the BAF complexes in genome stability
The PhD project is funded by a joint grant between the Luck and Schick lab from IMB as part of the second funding period of the CRC1361 on the regulation of DNA repair and genome stability. The grant aims to systematically investigate the role of BAF complexes in genome stability using a variety of techniques, including imaging-based screens, proteomics, genomics, CRISPR/Cas9 genome editing, functional assays and other molecular biology methods. The grant provides funding for a computational and an experimental PhD student, who will work closely together on the project. Here, we advertise for an experimental PhD position with the goal to obtain genome-wide views on the impact of BAF subunit perturbations on genome stability. To this end, the PhD candidate will use various next generation sequencing methods among which are state-of-the-art genomics approaches to map DNA lesions genome-wide. Integration of these with previously obtained results will enable generation of mechanistic hypotheses, which will be further investigated experimentally. Here, our goal is to focus on molecular mechanisms likely underlying tumor suppressive functions of BAF complexes.
We seek for a highly motivated, wet-lab experienced and science-enthusiastic PhD candidate who has a strong interest to approach scientific questions from a systems approach and in a collaborative team effort. The project is highly interdisciplinary and will be performed in close collaboration with the Luck lab, the core facilities from IMB and other groups of the CRC1361 (https://www.sfb1361.de).
If you are interested in this project, please select Schick as your group preference in the IPP application platform.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
We offer
For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
Activities and responsibilities
The research group of Ari Waisman offers the following PhD project:
The focus of this project is on the role of APCs in experimental autoimmune encephalomyelitis (EAE), a mouse model for the human autoimmune disease of the central nervous system (CNS) multiple sclerosis (MS). In EAE, dendritic cells (DCs) play an important role as they present a self-antigen to naive T cells and thereby prime them. The primed CD4+ T cells migrate to the CNS where they cross the blood brain barrier (BBB) and cause a demyelination of neurons and a disturbance of oligodendrocytes. In order to cross the BBB, the T cells must be reactivated. It is currently unknown which kind of APCs are involved in this process. A specific cell population we are interested in are the endothelial cells of the blood brain barrier (BBB). It was shown before that these cells are capable of expressing MHCII and therefore could play a role in the reactivation of T cells.
PhD project: Analysis of antigen-presenting cells interaction with T cells across the body during central nervous system autoimmunity
In the frame of this project, we will use a novel mouse system called “LIPSTIC” which can be used to label immune cell interactions. It was generated at the Rockefeller University In New York City and it will allow us to label and analyze in an unbiased manner all APCs in the CNS that are involved in the interaction with CD4+ T cells. It is based on the interaction between CD40, expressed by APCs, and CD40-ligand, expressed by T cells. When two cells interact with each other, a substrate is transferred from the T cell to the APCs which labels them and allows for visualization using flow cytometry.
The proposed project will make use of sophisticated mouse genetic systems, single cell sequencing and high dimensional flow cytometry as well as multiple cellular and molecular methods used in the lab.
If you are interested in this project, please select Waisman your group preference in the IPP application platform.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
We offer
For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
Activities and responsibilities
The research group of Carsten Deppermann offers the following PhD project:
Cardiovascular diseases (CVD) cause one third of all deaths worldwide. With increasing incidence of metabolic diseases in industrialized nations and emerging countries, a further global increase in cardiovascular diseases is expected in the future. Atherothrombosis is the main cause of heart attack and stroke and it has been established that platelets play an important role, which is why, in addition to the treatment of hyperlipidemia, e.g. with statins, dual antiplatelet therapy (DAPT) is now an important part of the standard treatment. Despite advances in the treatment of atherothrombosis, thrombotic events continue to occur even with optimal therapy. The aim of this project is to develop a novel therapeutic approach that focuses on the thromboinflammatory component of atherothrombosis. Together with our project partners, we want to generate anti-inflammatory platelets with an increased regenerative and reparative potential through RNA-based targeting of platelet precursors in the bone marrow (megakaryocytes).
PhD Project: Targeting megakaryocytes to generate reparative platelets in atherothrombosis
The aim of this project is the development of a novel therapeutic approach that specifically addresses the thrombo-inflammation component of atherothrombosis where multiple platelet functions are relevant: the local release of mediators stored in platelet granules and the stimulation/regulation of immune cells for wound healing and repair of the injured vessel wall. Together with our project partners, we aim to generate anti-inflammatory, reparative platelets by RNA-based targeting of platelet precursors (megakaryocytes). In the first project phase, our project partners will optimize nanodimensional lipid and polymer formulations for the specific targeting of megakaryocytes which will then be loaded with mRNA of selected targets. Using primary cell cultures of murine megakaryocytes and human iPSC-derived megakaryocytes, the candidate will investigate successful targeting of the megakaryocytes and transfer of the target proteins into mature platelets using flow cytometry and confocal microscopy. In the second phase of the project, we are planning in vivo experiments to verify successful megakaryocyte targeting in mice and to investigate the influence on atherothrombosis in relevant mouse models. In the long term, we plan to establish megakaryocyte/bone marrow targeting using mRNA nanoparticles as a new form of therapy and to investigate it in clinical studies.
If you are interested in this project, please select Deppermann as your group preference in the IPP application platform.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
We offer
For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
Activities and responsibilities
The research group of Axel Methner offers the following PhD project:
Mitochondria are crucial for cellular energy production, metabolism, and balance. The TOM complex facilitates protein import into mitochondria, which is vital for their function. Mitochondria-derived vesicles (MDVs) remove faulty TOM proteins, preserving mitochondrial health. The ubiquitin system, involving E3 ligases like MARCH5 and possibly MUL1/MAPL or PRKN, along with the DUB USP30, regulates this process, though specifics remain unclear. The relevance of this process for human disease is also still unclear.
Our project aims to decipher the ubiquitin code governing MDV-mediated quality control for mitochondrial import channels and its mechanistic implications. Aim 1 involves defining the ubiquitylation response in MDV formation through genetic approaches inducing TOM complex blockage. Aim 2 seeks to understand how ubiquitylation affects MDV formation by identifying functionally relevant ubiquitylation targets and manipulating their modification status. Aim 3 investigates the consequences of defective ubiquitin signaling on mitochondrial shape and function, clarifying its role in mitochondrial proteostasis.
Through cellular physiology measurements, genetic tools, and mutagenesis, we aim to uncover the mechanisms underlying MDV-mediated quality control and its impact on mitochondrial function and morphology. This research will provide insights into maintaining mitochondrial health and potential therapeutic targets for mitochondrial disorders.
PhD project: Contributions of ubiquitin signaling to the maintenance of mitochondrial import channels
The project is a collaborative project with the group of Helle Ulrich at the IMB Mainz and is funded within the DFG priority program Integration of mitochondria into the cellular proteostasis network” (SPP 2453). The priority program brings together 15 tandem groups in Germany with a common interest in the integration of mitochondria into the cellular proteostasis network and organizes meetings, summer schools etc. In tandem with the group of Helle Ulrich at the IMB, the Methnerlab will characterize different models for the induction of mitochondrial protein import clogging including an optogenetic model. We will also establish the visualization and quantification of MDVs in different physiological and also pathophysiological conditions. We will ultimately clarify the contributions of ubiquitin signaling to mitochondrial physiology upon clogging of mitochondrial import channels.
If you are interested in this project, please select Methner as your group preference in the IPP application platform.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
We offer
For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
Activities and responsibilities
The research group of Susann Schweiger offers the following PhD project:
Stress is a significant risk factor for the development of mental health problems, in particular depression and post traumatic stress disorder (PTSD). However, even after substantial stress exposure many people show resilience and do not develop severe mental health issues. We are using a mouse model for chronic social defeat stress to analyse the mechanisms underlying mental resilience.
As shown by several groups the permeability of the blood brain barrier (BBB) seems to play a critical role in mental resilience. Particularly in the nucleus accumbens and in the hippocampus exposure to chronic social defeat leads to an increase of the permeability of the BBB, which results in an entry of immune active cells into the brain parenchyma and is associated with an increase in susceptibility. In a single cell RNA sequencing of different parts of the hippocampus that we have carried out together with the groups of Beat Lutz and Susanne Gerber, has confirmed that it is the non-neuronal cells and the vascular endothelium in the dorsal hippocampus that are involved in adaptation processes after exposure to chronic social defeat stress.
PhD Project: Vascular factors that influence mental resilience
In further steps we are analysing the role of endothelial signaling, activated immune-cells and the coagulation system in mental resilience and susceptibility in response to stress. We are working in close collaboration with the group of Wolfram Ruf, an expert in vascular biology and Amparo Acker-Palmer from Frankfurt, who is experienced in the neurovascular niche. We are working with several stress models in mice.
If you are interested in this project, please select Schweiger (MetRes) as your group preference in the IPP application platform.
Qualification profile
Are you an ambitious, young scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start!
All you need is:
We offer
For more details on the projects offered and how to apply via our online form, please visit www.imb.de/phd.
The deadline for applications is 17 April 2024. Interviews will take place at IMB in Mainz on 1-3 July 2024.
Starting date: 1 August 2024 - 1 January 2025
At the Center for Molecular Bioengineering (B CUBE), an institute of the Center for Molecular and Cellular Bioengineering, the Junior Research Group Multi-scale Analysis (Dr. Igor Zlotnikov) offers a position as
Research Associate / PhD Student (m/f/x)
in Cross-scale characterization of biological biomineralized materials
(subject to personal qualification employees are remunerated according to salary group E 13 TV-L)
starting June 1, 2024. The position is initially limited for three years with the option of extension and entails 65% of the fulltime weekly hours. The period of employment is governed by the Fixed Term Research Contracts Act (Wissenschaftszeitvertragsgesetz - WissZeitVG). The position offers the chance to obtain further academic qualification (usually PhD).
Tasks: The main responsibilities will be to perform structural and compositional analysis of biomineralized structure across scales: from the sub-nanometer level to the level of the entire assembly employing electron microscopy-based and X-ray synchrotron-based techniques.
Requirements: university degree (master, diploma), preferably in the fields of biophysics, chemistry, materials science and mechanical engineering. Excellent communication skills in English are essential as this is the colloquial language at the research center. Qualifications should preferably include experience with electron microscopy, atomic force microscopy, X-Ray-based imaging and analysis.
For further information about the center see www.tu-dresden.de/bcube.
TUD strives to employ more women in academia and research. We therefore expressly encourage women to apply. The University is a certified family-friendly university and offers a Dual Career Service. We welcome applications from candidates with disabilities. If multiple candidates prove to be equally qualified, those with disabilities or with equivalent status pursuant to the German Social Code IX (SGB IX) will receive priority for employment.
Please submit your detailed application with the usual documents by April 12, 2024 (stamped arrival date or the time stamp on the email server of TUD applies) to: TU Dresden, Center for Molecular Bioengineering (B CUBE), Herrn Dr. Igor Zlotnikov, Tatzberg 41, 01307 Dresden, Germany or via the TUD SecureMail Portal https://securemail.tu-dresden.de by sending it as a single PDF file to katja.dornig@tu-dresden.de. Please submit copies only, as your application will not be returned to you. Expenses incurred in attending interviews cannot be reimbursed.
Reference to data protection: Your data protection rights, the purpose for which your data will be processed, as well as further information about data protection is available to you on the website: https://tu-dresden.de/karriere/datenschutzhinweis.
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An der Fakultät Maschinenwesen, Institut für Werkstoffwissenschaft, ist, vorbehaltlich vorhandener Mittel, an der Professur für Pulvermetallurgie zum 01.07.2024 eine Stelle als
wiss. Mitarbeiter:in (m/w/d)
(bei Vorliegen der persönlichen Voraussetzungen E 13 TV-L)
für 36 Monate (Beschäftigungsdauer gem. WissZeitVG), mit der Gelegenheit zur eigenen wiss. Weiterqualifikation (i.d.R. Promotion), zu besetzen.
Aufgaben:
Voraussetzungen: wiss. Hochschulabschluss der Fachrichtung Werkstoffwissenschaft.
Die TUD strebt eine Erhöhung des Anteils von Frauen an und bittet diese deshalb ausdrücklich um deren Bewerbung. Die Universität ist eine zertifizierte familiengerechte Hochschule und verfügt über einen Dual Career Service. Bewerbungen schwerbehinderter Menschen sind besonders willkommen. Bei gleicher Eignung werden diese oder ihnen Kraft SGB IX von Gesetzes wegen Gleichgestellte bevorzugt eingestellt.
Ihre aussagekräftige Bewerbung senden Sie bitte mit den üblichen Unterlagen bis zum 30.05.2024 (es gilt der Poststempel der Zentralen Poststelle bzw. der Zeitstempel auf dem E-Mail-Server der TUD) an: TU Dresden, Fakultät Maschinenwesen, Institut für Werkstoffwissenschaft, Professur für Pulvermetallurgie, Herrn Prof. Dr.-Ing. Thomas Weißgärber, Helmholtzstr. 10, 01069 Dresden oder über das SecureMail Portal der TUD https://securemail.tu-dresden.de in einem PDF–Dokument an thomas.weissgaerber@tu-dresden.de. Ihre Bewerbungsunterlagen werden nicht zurückgesandt, bitte reichen Sie nur Kopien ein. Vorstellungskosten werden nicht übernommen.
Hinweis zum Datenschutz: Welche Rechte Sie haben und zu welchem Zweck Ihre Daten verarbeitet werden sowie weitere Informationen zum Datenschutz haben wir auf der Webseite https://tu-dresden.de/karriere/datenschutzhinweis für Sie zur Verfügung gestellt.
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An der Fakultät Chemie und Lebensmittelchemie ist an der Professur für Physikalische Organische Chemie zum 01.08.2024 eine Stelle als
wiss. Mitarbeiter:in / Doktorand:in (m/w/d)
(bei Vorliegen der persönlichen Voraussetzungen E 13 TV-L)
für drei Jahre (Beschäftigungsdauer gem. WissZeitVG), mit 50% der regelmäßigen wöchentlichen Arbeitszeit und dem Ziel der eigenen wiss. Weiterqualifikation (i.d.R. Promotion), zu besetzen.
Aufgaben: wiss. Lehr-u. Forschungstätigkeiten, selbstständige und kooperative Qualifikation durch eine wiss. Forschungstätigkeit auf dem Gebiet der metallorganischen Chemie; Synthese und Anwendung neuer metallorganischer Verbindungen, insb. der späten Übergangsmetalle zur Untersuchung angeregter Zustände, zur Anwendung als Emitter in OLEDs und als Katalysatoren für verschiedene Reaktionen; Synthese neuer heterozyklischer Liganden und Matrixmaterialien zur Variation der Eigenschaften der OLEDs; Anwendung neuer ionischer Flüssigkeiten in der Katalyse; Einarbeitung in die fachspezifischen Aufgabenstellungen durch Literaturstudien und Präzisierung der individuellen Zielsetzung; Bearbeitung des Promotionsprojektes in engem Austausch mit potentiellen Projektpartnern; Durchführung der jeweils geplanten Untersuchungen, Auswertung und Interpretation der Ergebnisse; Erarbeitung und Darstellung neuen Wissens in dem Forschungsfeld; Teilnahme an Veranstaltungen des Arbeitskreises und Workshops; Unterstützung von wiss. Graduierungsarbeiten (Bachelor/Master/Diplom); regelmäßige Berichterstattung über die eigenen Forschungsfortschritte gegenüber den wiss. Betreuern:innen; Veröffentlichung der Ergebnisse der Forschungsarbeiten in individuellen und kooperativen Publikationen; Pflege von Austauschplattformen (Datenbank, Informationsseiten, Internet); Pflege der analytischen Geräte.
Voraussetzungen: sehr guter wiss. Hochschulabschluss (MSc., Dipl.) in Chemie; vertiefte Kenntnisse der organischen Chemie, idealerweise Erfahrungen mit Schutzgaschemie auf dem Gebiet der metallorganischen Chemie und der Katalyse sowie mit quantenchemischen Rechnungen (Gaussian16, ORCA); hohe Motivation und Fähigkeit zum kreativen und eigenständigen Arbeiten; Bereitschaft zur Integration in das bestehende Team sowie zur Übernahme von Verantwortung. Es stehen eine Vielzahl verschiedener Forschungsthemen zur Auswahl, daher sind wir auf der Suche nach erstklassigen Hochschulabsolvent:innen mit exzellenten Fachkenntnissen im Gebiet der Organischen Chemie, hohem fachübergreifendem Lernwillen und Kooperationsbereitschaft, sehr guten mündlichen und schriftlichen Kommunikationsfähigkeiten in der deutschen und englischen Sprache und der wiss. Publikation in Wort und Schrift.
Die TUD strebt eine Erhöhung des Anteils von Frauen an und bittet diese deshalb ausdrücklich um deren Bewerbung. Die Universität ist eine zertifizierte familiengerechte Hochschule und verfügt über einen Dual Career Service. Bewerbungen schwerbehinderter Menschen sind besonders willkommen. Bei gleicher Eignung werden diese oder ihnen Kraft SGB IX von Gesetzes wegen Gleichgestellte bevorzugt eingestellt.
Ihre aussagekräftige Bewerbung senden Sie bitte mit den üblichen Unterlagen bis zum 05.04.2024 (es gilt der Poststempel der Zentralen Poststelle bzw. der Zeitstempel auf dem E-Mail-Server der TUD) bevorzugt über das SecureMail Portal der TUD https://securemail.tu-dresden.de in einem PDF–Dokument an thomas.strassner@tu-dresden.de bzw. an: TU Dresden, Fakultät Chemie und Lebensmittelchemie, Professur für Physikalische Organische Chemie, Herrn Prof. Thomas Straßner, Helmholtzstr. 10, 01069 Dresden. Ihre Bewerbungsunterlagen werden nicht zurückgesandt, bitte reichen Sie nur Kopien ein. Vorstellungskosten werden nicht übernommen.
Hinweis zum Datenschutz: Welche Rechte Sie haben und zu welchem Zweck Ihre Daten verarbeitet werden sowie weitere Informationen zum Datenschutz haben wir auf der Webseite https://tu-dresden.de/karriere/datenschutzhinweis für Sie zur Verfügung gestellt.
]]>Im Rahmen der aktuellen Ausschreibung bietet die Klasse für Literatur zum Wintersemester 2024/25 eine Promotionsstelle (TV-L 13, 50 %, bis zu 3 Jahre, Besetzung voraussichtlich ab dem 01.10.2024) für exzellente BewerberInnen aus dem In- und Ausland.
Das Promotionsprogramm bietet außerdem exklusiv für internationale Promovierende ein attraktives GSSP-Stipendium (DAAD) für bis zu vier Jahre. Mehr Informationen zum Stipendium finden sich hier: https://www.daad.de/de/infos-services-fuer-hochschulen/weiterfuehrende-infos-zu-daad-foerderprogrammen/gssp/
Bewerbungsfrist: 1. Mai 2024
Bewerbungsportal: https://www.prolit.uni-muenchen.de/bewerbung/index.html
]]>Am Standort Dresden befindet sich mit „Silicon Saxony“ das größte Mikroelektronikcluster Europas.
An der Fakultät Elektrotechnik und Informationstechnik,Institut für Grundlagen der Elektrotechnik und Elektronik, ist, vorbehaltlich vorhandener Mittel, an der Professur für Schaltungstechnik und Netzwerktheorie (PSN) zum nächstmöglichen Zeitpunkt eine Stelle als
wiss. Mitarbeiter:in / Doktorand:in (m/w/d)
im Gebiet Design von Hochfrequenz-Leistungsverstärker-Chips inkl. Open-Source-IC-Design
(bei Vorliegen der persönlichen Voraussetzungen E 13 TV-L)
zunächst bis 30.04.2027 (Beschäftigungsdauer gem. WissZeitVG) zu besetzen. Es besteht die Gelegenheit zur eigenen wiss. Weiterqualifikation (i. d. R. Promotion).
Die Arbeiten erfolgen insb. im Rahmen des vom Bundesministerium für Bildung und Forschung geförderten Projektes DI-DEMICO. In DI-DEMICO sollen Millimeterwellen-Schaltungen erstmals mittels Open-Source-Tools entworfen werden. Das Open-Source-IC-Design ist ein sehr wichtiges und attraktives Thema für deutsche Firmen und Start-ups, u.a. aufgrund der signifikanten Kosteneinsparungen beim Design. Die Stelle bietet eine sehr gute Plattform für die interdisziplinäre Zusammenarbeit mit Partnern sowie die Möglichkeit, Ihre persönliche Entwicklung maßgeblich zu fördern.
Das Teilprojekt der Professur für Schaltungstechnik und Netzwerktheorie fokussiert sich auf das Design von neuartigen, rekonfigurierbaren 60 GHz Verstärker-Chips in IHP BiCMOS mit zwei Ausgangsleistungsmoden (12 dBm und 0 dBm) für die energieeffiziente, umweltfreundliche sehr schnelle 6G-Kommunikationstechnik der Zukunft, sowie das Design von Hochfrequenz-Baugruppen mittels Open-Source-Software.
Die Professur für Schaltungstechnik und Netzwerktheorie widmet sich als eine führende Professur im Gebiet der integrierten Schaltungstechnik dem Entwurf und der Modellierung von hocheffizienten, integrierten Hochfrequenz- und Mixed-Signal-Schaltungen. Die Anwendungen umfassen insb. die drahtlose und drahtgebundene 5G- und 6G-Informations- und Kommunikationstechnik sowie Sensorsysteme der Zukunft.
Aufgaben: Erforschung, Entwurf, Analyse, Optimierung, Implementierung, Vergleich und Messung von integrierten Hochfrequenz-Schaltungskomponenten mit Fokus auf adaptive 60 GHz Leistungsverstärker. Auf Basis einer neuartigen rekonfigurierbaren Architektur sollen diese Leistungsverstärker die Anpassung der Ausgangsleistung bei hoher Effizienz ermöglichen. Perspektivisch kann dadurch mittels KI-Assistenz beim Betrieb massiv Energie eingespart werden. Zusätzlich zu Standard-Werkzeugen, die als Referenz dienen, wie z.B. Cadence, sollen Open-Source-IC-Design-Werkzeuge und Designkits eingesetzt, untersucht und in Kooperation mit den Partnern Beiträge für deren Verbesserungen geleistet werden. Sie werden wiss. Publikationen erarbeiten sowie an Projekttreffen und Konferenzen teilnehmen.
Voraussetzungen: Gesucht wird ein:e Kandidat:in mit einem sehr guten oder guten ingenieurwiss. Hochschulabschluss (Universität) in Elektrotechnik, Kommunikationstechnik oder Informationstechnik mit Kenntnissen im Gebiet der Schaltungs-, Hochfrequenz-, Halbleiter- sowie Nachrichtentechnik. Neugierde für neue Technologien, selbständige und flexible Arbeitsweise, Kommunikations- und Teamfähigkeit, gutes Englisch, innovatives und analytisches Denken und hohen Einsatz setzen wir voraus. Kenntnisse bzgl. der Nutzung von CAD-IC-Design-Tools sowie Schaltungssimulationen und Chiplayouts sind hilfreich.
Die TUD strebt eine Erhöhung des Anteils von Frauen an und bittet diese deshalb ausdrücklich um deren Bewerbung. Die Universität ist eine zertifizierte familiengerechte Hochschule und verfügt über einen Dual Career Service. Bewerbungen schwerbehinderter Menschen sind besonders willkommen. Bei gleicher Eignung werden diese oder ihnen Kraft SGB IX von Gesetzes wegen Gleichgestellte bevorzugt eingestellt.
Ihre vollständigen Bewerbungsunterlagen, einschl. Lebenslauf und Zeugniskopien, senden Sie bitte bis zum 15.04.2024 (es gilt der Poststempel der Zentralen Poststelle bzw. der Zeitstempel auf dem E-Mail-Server der TUD) bevorzugt über das SecureMail Portal der TUD https://securemail.tu-dresden.de in einem PDF-Dokument an frank.ellinger@tu-dresden.de bzw. an: TU Dresden, Fakultät Elektrotechnik und Informationstechnik, Institut für Grundlagen der Elektrotechnik und Elektronik, Professur für Schaltungstechnik und Netzwerktheorie, Herrn Prof. Frank Ellinger, Helmholtzstr. 10, 01069 Dresden. Ihre Bewerbungsunterlagen werden nicht zurückgesandt, bitte reichen Sie nur Kopien ein. Vorstellungskosten werden nicht übernommen.
Hinweis zum Datenschutz: Welche Rechte Sie haben und zu welchem Zweck Ihre Daten verarbeitet werden sowie weitere Informationen zum Datenschutz haben wir auf der Webseite https://tu-dresden.de/karriere/datenschutzhinweis für Sie zur Verfügung gestellt.
]]>Das Projekt wird eine Kombination aus numerischer Modellierung von Terahertz-Metasurface-Resonatoren, lithographischer Herstellung und gepulsten Elektronenspinresonanz-Experimenten umfassen.
Die Stelle kann sofort angetreten werden und ist auf 3-4 Jahre befristet. Die Vergütung erfolgt in Anlehnung an den Tarifvertrag für den Öffentlichen Dienst der Länder (TV-L E13 50%).
Gesucht werden hochmotivierte Personen mit einem MSc in Physik oder Physikalischer Technik o.ä., die Interesse an multidisziplinären Projekten an der Schnittstelle von Physik, Chemie, Material- und Ingenieurwissenschaften haben. Idealerweise, aber nicht notwendigerweise, verfügt der Bewerber über Erfahrung mit Metamaterialien oder Metaoberflächen und/oder Terahertz-Zeitbereichsspektroskopie und/oder magnetischen Resonanztechniken.
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An der Fakultät Verkehrswissenschaften “Friedrich List“, Institut für Bahnsysteme und Öffentlichen Verkehr, ist an der Professur für Betrieb von Bahnsystemen zum nächstmöglichen Zeitpunkt eine Stelle als
wiss. Mitarbeiter:in (m/w/d)
(bei Vorliegen der persönlichen Voraussetzungen E 13 TV-L)
für 3 Jahre bis max. 31.05.2027 mit der Option der Verlängerung (Beschäftigungsdauer gem. WissZeitVG) und der Gelegenheit zur eigenen wiss. Weiterqualifikation (i. d. R. Promotion) zu besetzen. Die Vereinbarkeit von Familie und Beruf hat einen hohen Stellenwert. Die Stelle ist grundsätzlich auch für Teilzeitbeschäftigte geeignet. Bitte vermerken Sie diesen Wunsch in Ihrer Bewerbung.
In unseren vielfältigen Forschungsprojekten auf dem Gebiet der Eisenbahnbetriebswissenschaften untersuchen wir grundlegende systemische Wirkungszusammenhänge, entwickeln die darauf aufbauenden theoretischen Verfahren weiter und überführen diese in Lösungen für die verkehrliche und betriebliche Praxis. Wesentliche Schwerpunkte bilden dabei die Gebiete Leistungsfähigkeit, Betriebsqualität und Betriebsplanung sowie die Entwicklung und Modellierung zukunftsfähiger Betriebsprozesse und Technologien für den Personen- und den Güterverkehr. So wird im Projekt REINFORCERAIL eine KI-unterstützte Komponente für Verkehrsmanagementsysteme im Bahnbetrieb entwickelt. Dafür steht auch eine Modelleisenbahnsimulation im Eisenbahnbetriebslabor (EBL) der TU Dresden zur Verfügung. Das EBL bietet sowohl eine computergestützte Simulation als auch eine physische Umgebung zur Demonstration, in der Zugbewegungen, Signalisierung und Verkehrsbetrieb realistisch modelliert werden. Dabei werden urbane und konventionelle Bahnsysteme kombiniert.
Aufgaben: Ihre Tätigkeit umfasst in diesem Kontext schwerpunktmäßig Folgendes:
Voraussetzungen:
Wir bieten Ihnen:
Die TUD strebt eine Erhöhung des Anteils von Frauen an und bittet diese deshalb ausdrücklich um deren Bewerbung. Die Universität ist eine zertifizierte familiengerechte Hochschule und verfügt über einen Dual Career Service. Bewerbungen schwerbehinderter Menschen sind besonders willkommen. Bei gleicher Eignung werden diese oder ihnen Kraft SGB IX von Gesetzes wegen Gleichgestellte bevorzugt eingestellt.
Bei Fragen wenden Sie sich bitte an Herrn Prof. Nikola Bešinović unter nikola.besinovic@tu-dresden.de.
Ihre aussagekräftige Bewerbung senden Sie bitte mit den üblichen Unterlagen bis zum 03.04.2024 (es gilt der Poststempel der Zentralen Poststelle bzw. der Zeitstempel auf dem E-Mail-Server der TUD) bevorzugt über das SecureMail Portal der TUD https://securemail.tu-dresden.de in einem PDF-Dokument an bsrv@tu-dresden.de bzw. an: TU Dresden, Fakultät Verkehrswissenschaften “Friedrich List“, Institut für Bahnsysteme und Öffentlichen Verkehr, Professur für Betrieb von Bahnsystemen, Herrn Prof. Nikola Bešinović, Helmholtzstr. 10, 01069 Dresden. Ihre Bewerbungsunterlagen werden nicht zurückgesandt, bitte reichen Sie nur Kopien ein. Vorstellungskosten werden nicht übernommen.
Hinweis zum Datenschutz: Welche Rechte Sie haben und zu welchem Zweck Ihre Daten verarbeitet werden sowie weitere Informationen zum Datenschutz haben wir auf der Webseite https://tu-dresden.de/karriere/datenschutzhinweis für Sie zur Verfügung gestellt.
]]>Die 11 Promotionsstipendien verteilen sich auf vier Themengebiete:
Mechanisms of viral infection
P2: Investigation of the antiphage properties of aminoglycoside antibiotics and impact of bacterial (self-)resistance mechanisms (Julia Frunzke, Bacterial Networks and Interactions, FZ Jülich)
P3: How do hepatitis viruses reprogramme the host cell response to inflammatory cytokines? (Johannes Bode, Tom Lüdde, Klinik für Gastroenterologie, Hepatologie und Infektiologie Universitätsklinikum Düsseldorf)
P4: Regulation of KIR3DL1 gene expression and functional consequences for the antiviral activity of NK cells (Jörg Timm, Institute for Virology, Heinrich Heine University Düsseldorf)
Bacterial proteins in infection and infection control
P5: Integrative structure-function analysis of the RTX toxin MbxA from Moraxella bovis (Lutz Schmitt, Chair of Biochemistry I, HHU Düsseldorf)
P7: Studies on the redundant role of highly redundant small non-coding RNAs in Mycobacterium tuberculosis (Rainer Kalscheuer, Institute of Pharmaceutical Biology and Biotechnology, HHU Düsseldorf)
Molecular regulatory mechanisms in fungi
P10: The role of the microtubule cytoskeleton in infection processes (Ursula Fleig, Eukaryotic Microbiology, HHU Düsseldorf)
Control of immune response to infection
P12: Functional analysis of lymphotoxin-β receptor-dependent effector mechanisms during the immune response against intracellular pathogens (Prof. Klaus Pfeffer, Dr. Daniel Degrandi, Institute of Medical Microbiology and Hospital Hygiene, HHU Düsseldorf)
P13: Functional fine-mapping of HLA- and KIR-mediate Hepatitis C immune control through long-read sequencing and single-cell transcriptomics (Alexander Dilthey, Institute of Medical Microbiology and Hospital Hygiene, HHU Düsseldorf)
P16: The impact of Tspan2 on differentiation and function of neutrophils in anti-infectious immune responses (Stefanie Scheu, Institute of Medical Microbiology and Hospital Hygiene, HHU Düsseldorf)
P17: The role of the purinergic receptor P2X7 for cross-presentation of antigens during poxviral infection (Ingo Drexler, Institute for Virology, HHU Düsseldorf)
P18: The role of cellular membrane bodies during viral infection (Philipp A. Lang, Department of Molecular Medicine II, University Hospital Düsseldorf)
Die Dissertationsprojekte sind inhaltlich und methodisch untereinander vernetzt. Im Rahmen des Qualifizierungsprogramms von MOI-V gewinnen die Doktorandinnen und Doktoranden in Vorlesungen, Seminaren und Praktika einen umfassenden Einblick in die Infektionsbiologie der drei großen Erregergruppen Viren, Bakterien und Pilze/Protozoen sowie der Immunantwort der Wirtszelle. Im weiteren Studienprogramm werden umfangreiche berufsqualifizierende Schlüsselkompetenzen vermittelt. Ein Auslandsaufenthalt ist integraler Bestandteil der Promotionsprojekte. Jährliche MOI Symposien bieten die Plattform zur Präsentation der Forschungsergebnisse und zum intensiven wissenschaftlichen Austausch. Ein internationaler Wissenschaftlicher Beirat begleitet MOI-V und unterstützt die Doktorandinnen und Doktoranden in ihren Promotionsprojekten.
Die Heinrich-Heine-Universität ist mit mehr als 34.000 Studierenden das Zentrum des Universitätsstandortes Düsseldorf. Als Volluniversität mit den fünf Fakultäten Jura, Ökonomie, Geistenwissenschaften, Medizin und Mathematik & Naturwissenschaften fördert die HHU enge interdisziplinäre Kooperationen auf regionalem, nationalem und internationalem Niveau. Die HHU wurde bereits zum dritten Mal mit dem TOTAL E-Quality-Prädikat ausgezeichnet.
Hier können Sie sich die notwendigen Unterlagen für Ihre Bewerbung herunterladen: https://www.moi.hhu.de/stellenangebote
Bei Fragen wenden Sie sich bitte per E-Mail an die wissenschaftliche Koordinatorin, Dr. Stephanie Spelberg (moi@hhu.de).
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At the Faculty of Electrical and Computer Engineering, Institute of Circuits and Systems, the Chair of Measurement and Sensor System Technique (Czarske Lab, www.tu-dresden.de/et/mst/) offers a position as
Research Associate / PhD Student (m/f/x)
Diffractive Neural Networks for Fiber-optical Information Processing
(subject to personal qualification employees are remunerated according to salary group E 13 TV-L)
starting as soon as possible. The position is limited to 30 months. The period of employment is governed by the Fixed Term Research Contracts Act (Wissenschaftszeitvertragsgesetz - WissZeitVG). The position offers the chance to obtain further academic qualification (usually PhD).
Fiber-optical networks are the backbone of the global internet infrastructure. However, multimode fibers provide additional channels for data transmission by multiplane light conversion. The goal is to exploit novel optical diffractive neural networks for high fidelity space division multiplexing. The optical neural networks operate with high speed, low latency, and low energy consumption (non von-Neumann architecture).
Tasks: Innovative concepts for light control in multimode fibers are investigated towards (de)multiplexing of optical states via the spatial degrees of freedom. High-dimensional quantum states (qudits) will be included. Your activities include the realization of multimode fiber systems with diffractive neural networks, the characterization of the light transmission properties and the transfer to applications.
Requirements: above-average university degree in the subject electrical engineering, computer science, physics or related areas; ability and willingness to work independently and conceptually in a dynamic team; curiosity in research at interfaces of sciences Interest in practice-oriented, interdisciplinary cooperation with partners from research and industry; knowledge of software development and digital signal processing. Previous knowledge of AI/ML/DNN, technical optics, quantum optics, MATLAB or Python is advantageous.
We offer: Living and success in Florence at the Elbe; Laboratories with modern equipment, excellent contacts in research and industry, visiting international conferences and an interdisciplinary, flexible team.
Technical questions will be answered with pleasure: juergen.czarske@tu-dresden.de.
TUD strives to employ more women in academia and research. We therefore expressly encourage women to apply. The University is a certified family-friendly university and offers a Dual Career Service. We welcome applications from candidates with disabilities. If multiple candidates prove to be equally qualified, those with disabilities or with equivalent status pursuant to the German Social Code IX (SGB IX) will receive priority for employment.
Please submit your detailed application with the usual documents by April 10, 2024 (stamped arrival date of the university central mail service or the time stamp on the email server of TUD applies) to: TU Dresden, Fakultät Elektrotechnik und Informationstechnik, Institut für Grundlagen der Elektrotechnik und Elektronik, Professur für Mess- und Sensorsystemtechnik, Herrn Prof. Dr.-Ing. habil. J. Czarske, Helmholtzstr. 10, 01069 Dresden, Germany or as a single pdf file to grp-mst-sekretariat@msx.tu-dresden.de (Please note: We are currently not able to receive electronically signed and encrypted data.). Please submit copies only, as your application will not be returned to you. Expenses incurred in attending interviews cannot be reimbursed.
Reference to data protection: Your data protection rights, the purpose for which your data will be processed, as well as further information about data protection is available to you on the website: https://tu-dresden.de/karriere/datenschutzhinweis.
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An der Fakultät Elektrotechnik und Informationstechnik, Elektrotechnisches Institut, ist an der Professur für Elektrische Maschinen und Antriebe zum nächstmöglichen Zeitpunkt eine Stelle als
wiss. Mitarbeiter:in (m/w/d)
(bei Vorliegen der persönlichen Voraussetzungen E 13 TV-L)
für 36 Monate (Beschäftigungsdauer gem. WissZeitVG) zu besetzen. Eine weitere bis zu zweijährige Verlängerung des Forschungsprojekts im Rahmen einer Promotionsarbeit wird angestrebt.
Aufgaben: Im Rahmen eines DFG-Projektes ist die Thematik „Erwärmung und Kühlung von Asynchronmaschinen für hochdynamische Anwendungen“ wiss. zu bearbeiten. Zur Lösung der Aufgabe sind Untersuchungen zum magnetischen und thermischen Verhalten ausgewählter Rotorkonstruktionen durchzuführen bzw. Vorschläge zu deren Verbesserung zu erarbeiten. Die theoretischen Arbeiten werden durch numerische 2D/3D-Simulationen unterstützt. Zur Verifikation der Ergebnisse soll ein prototypisches Modell entwickelt und die Wirksamkeit der Kühlmaßnahmen messtechnisch nachgewiesen werden. Die Arbeiten finden in enger Kooperation mit Strömungsmechaniker:innen der Universität statt.
Voraussetzungen: wiss. Hochschulabschluss (Diplom o. Master) der Elektrotechnik oder Mechatronik mit dem Schwerpunkt Elektrische Maschinen. Grundkenntnisse im Umgang mit FE-Modellierung und –Simulation sind von Vorteil. Die Fähigkeit zu selbständigem und zielorientiertem Arbeiten mit Interesse an interdisziplinärer Zusammenarbeit im Team mit Maschinenbauer:innen wird geschätzt.
Wir bieten: eine anspruchsvolle, abwechslungsreiche und hochaktuelle Forschungstätigkeit mit individuellen Gestaltungsmöglichkeiten, Besuch internationaler Fachtagungen für den wiss. Austausch, gute Kontakte zu Partnern aus Forschung und Industrie, Qualifikation zum:zur Doktoringenieur:in.
Die TUD strebt eine Erhöhung des Anteils von Frauen an und bittet diese deshalb ausdrücklich um deren Bewerbung. Die Universität ist eine zertifizierte familiengerechte Hochschule und verfügt über einen Dual Career Service. Bewerbungen schwerbehinderter Menschen sind besonders willkommen. Bei gleicher Eignung werden diese oder ihnen Kraft SGB IX von Gesetzes wegen Gleichgestellte bevorzugt eingestellt.
Ihre aussagekräftige Bewerbung senden Sie bitte mit den üblichen Unterlagen bis zum 10.04.2024 (es gilt der Poststempel der Zentralen Poststelle bzw. der Zeitstempel auf dem E-Mail-Server der TUD) an: TU Dresden, Fakultät Elektrotechnik und Informationstechnik, Elektrotechnisches Institut, Professur für Elektrische Maschinen und Antriebe, Herrn Prof. Wilfried Hofmann, Helmholtzstr. 10,01069 Dresden oder über das SecureMail Portal der TUD https://securemail.tu-dresden.de in einem PDF-Dokument an wilfried.hofmann@tu-dresden.de. Ihre Bewerbungsunterlagen werden nicht zurückgesandt, bitte reichen Sie nur Kopien ein. Vorstellungskosten werden nicht übernommen.
Hinweis zum Datenschutz: Welche Rechte Sie haben und zu welchem Zweck Ihre Daten verarbeitet werden sowie weitere Informationen zum Datenschutz haben wir auf der Webseite https://tu-dresden.de/karriere/datenschutzhinweis für Sie zur Verfügung gestellt.
]]>wissenschaftliche:n Mitarbeiter:in (w/m/d)
(Entgeltgruppe 13 TV-L, 100 %)
Das Fachgebiet Werkstoffe der Elektrotechnik ist eingebunden in das Zentrum für NanoIntegration der Universität Duisburg-Essen (CENIDE), welches mit ca. 80 Arbeitsgruppen die Nanowissenschaften an der Universität bündelt.
Ihre Aufgaben
Ihr Profil
Im Rahmen der Tätigkeit wird Gelegenheit zur wissenschaftlichen Weiterqualifikation geboten.
]]>Starting from October 01, 2024, the Sino-German International Research Training Group AMAIZE-P offers
13 positions for doctoral researchers (PhD students) - (all genders welcome)
at the University of Hohenheim for candidates with above-average graded master's degrees or corresponding qualifications. The positions are limited to a maximum of 3 years. The salary follows the German public service pay scale TV-L E13 65% for doctoral researchers (PhD students) and TV-L E13 100% for postdoctoral researchers. The following research subjects (RS) are available:
1. Genetic potential of maize:
- RS 1.1 Dissecting the genetic architecture of phosphorus-use efficiency in maize (Prof. Dr. Tobias Würschum)
- RS 1.2 Loss of key repressors of the N and P-acquisition improves maize yield under low nutrient supply (Prof. Dr. Uwe Ludewig)
- RS 1.3 Integrative "Omics" analysis of carbohydrate metabolism and transport in response to low phosphate supply (Prof. Dr. Waltraud Schulze)
2. Management at field and farm level:
- RS 2.1 Genotype to phenotype modelling for locally adapted P-efficient maize ideosystems (Prof. Dr. Simone Graeff-Hönninger)
- RS 2.2 Closing phosphate cycles at the regional level with innovative fertilization strategies including recycling fertilizers – pot and field trials, long-term scenarios (Prof. Dr. Torsten Müller)
- RS 2.3 Detecting P status of maize through machine learning based on 3D imaging at the field scale (Prof. Dr. Joachim Müller)
- RS 2.4 Uptake and allocation of heavy metals from P-fertilizers along the soil-plant-atmosphere continuum (Jun.-Prof. Dr. Andreas Schweiger)
3. Nutrition and recovery:
- RS 3.1 Atherogenic properties of fresh and stored foods from maize grown under different P-availability conditions (Prof. Dr. Jan Frank)
- RS 3.2 Relevance of phytate-P and phytase content in pig microbiome functionality and host interaction (Prof. Dr. Amélia Camarinha Silva)
- RS 3.3 Energetic and chemical optimization of a laboratory system for P recovery in mid to small-sized farms (Dr. Hans Oechsner & Prof. Dr. Joachim Müller)
- RS 3.4 Phosphate recovery by hydrothermal carbonization: process simulation and scale-up (Prof. Dr. Andrea Kruse)
4. Economic evaluation and synthesis:
- RS 4.1 Assessment of ecosystem services of novel and innovative P-efficient maize-based food-feed-energy systems with a modelling approach (Prof. Dr. Enno Bahrs)
- RS 4.3 Assessing the implications of future P-availability for global agri-food markets using a Computable General Equilibrium modelling approach (Dr. Kirsten Boysen-Urban)
Detailed information about the Sino-German International Research Training Group AMAIZE-P and the single research subjects (RS) may be found on the project website: https://amaize-p.uni-hohenheim.de
The project requires extended research stays in China of up to three months per year. With equal qualifications, preference will be given to candidates with disabilities. The University of Hohenheim seeks to increase the proportion of women in research and teaching, therefore strongly encouraging female researchers to apply.
Applications in English language indicating a preference for one or a maximum of two of the topics mentioned above, letter of motivation, CV, copies of certificates, and proof of very good English language skills (corresponding to TOEFL ibt 90 or IELTS grade 6.5) are expected to be sent via e-mail as one entire pdf document by May 01, 2024, 24:00 h CEST (22:00 h UTC) to the coordinator (German side) of the Sino-German International Research Training Group:
Dr. Marco Roelcke, University of Hohenheim (763), 70593 Stuttgart, Germany
Phone: +49 711 45923984, e-mail: marco.roelcke@uni-hohenheim.de
Scientific Background:
The quality of human (and veterinary) health care systems substantially depends on key innovations. Often, these were driven by the field of physics, followed by interdisciplinary and inter-sectorial actions in engineering, chemistry, biology, and medicine. By using beyond state-of-the-art plasma multijet technology, the primary technical objective of PlasmACT is to support skin cancer prevention by medical gas plasma therapy of Actinic Keratosis.
Short overview of PlasmACT:
The PlasmACT Doctoral Network brings together 5 beneficiaries and 10 associated partners, located in 5 different countries (Germany, France, Netherlands, Belgium, and Luxembourg). Eight Doctoral candidates will enjoy a multi-disciplinary and international environment with plenty of training opportunities and exchange with all institutions involved in the network.
Eligibility criteria:
Bewerbungsfrist: 1. Mai 2024
Die Klasse bietet ein forschungsorientiertes und vernetztes Lehrprogramm, das aus allen Fachdidaktiken der Fakultät für Sprach- und Literaturwissenschaften der LMU München gespeist wird. Hochschullehrer:innen aus der Deutsch- und Englischdidaktik, den Didaktiken der romanischen und der klassischen Sprachen vertreten ein breites Spektrum theoretischer Positionen, forschungsmethodologischer Ansätze und unterschiedlicher Praxisbezüge. Die Interdisziplinarität des Veranstaltungsangebots fokussiert Prozesse und Ergebnisse des Lehrens und Lernens von Sprache, Literatur und Kultur in Erst-, Zweit- und Fremdsprachen in schulischen und außerschulischen Kontexten.
Dissertationsvorhaben können historische, theoretische oder empirische Fragestellungen der Sprach-, Literatur- oder Mediendidaktik sowie der Unterrichtsforschung behandeln. Promovierende der Class of Language Education profitieren von einer intensiven und individuellen Betreuung ihres Promotionsvorhabens, einem interessanten Gastprogramm, der Vermittlung von Schlüsselqualifikationen sowie von vielfältigen Möglichkeiten zum fachlichen Austausch und der finanziellen Unterstützung für Forschungs- und Kongressreisen.
Erwartet werden ein überdurchschnittlicher Hochschulabschluss, (Staatsexamen, state board examination, Magister Artium, diploma, Master of Arts, Maîtrise, Laurea, etc.) in einem der folgenden (didaktisch) ausgerichteten Fächer: Anglistik, Amerikanistik, Germanistik, Romanistik, Klassische Philologie, Sprachlehrforschung. Zudem werden hinreichende Kenntnisse in mindestens zwei europäischer Wissenschaftssprachen, darunter Deutsch (min. B1), sowie Teamfähigkeit und die Bereitschaft, sich aktiv in die Klasse einzubringen, vorausgesetzt.
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An der Fakultät Informatik, Institut für Technische Informatik, ist an der Professur für Rechnerarchitektur zum nächstmöglichen Zeitpunkt eine Stelle als
wiss. Mitarbeiter:in / Doktorand:in (m/w/d)
(bei Vorliegen der persönlichen Voraussetzungen E 13 TV-L)
mit 50% der regelmäßigen wöchentlichen Arbeitszeit, für 3 Jahre mit der Option auf Verlängerung (Beschäftigungsdauer gem. WissZeitVG) und Erhöhung der Arbeitszeit sowie dem Ziel der eigenen wiss. Weiterqualifikation (i.d.R. Promotion), zu besetzen.
Aufgaben:
Voraussetzungen:
Die TUD strebt eine Erhöhung des Anteils von Frauen an und bittet diese deshalb ausdrücklich um deren Bewerbung. Die Universität ist eine zertifizierte familiengerechte Hochschule und verfügt über einen Dual Career Service. Bewerbungen schwerbehinderter Menschen sind besonders willkommen. Bei gleicher Eignung werden diese oder ihnen Kraft SGB IX von Gesetzes wegen Gleichgestellte bevorzugt eingestellt.
Ihre aussagekräftige Bewerbung senden Sie bitte mit den üblichen Unterlagen unter Angabe der Stellenkennung „RA-Lehre Data Analytics“ bis zum 10.04.2024 (es gilt der Poststempel der Zentralen Poststelle bzw. der Zeitstempel auf dem E-Mail-Server der TUD) bevorzugt über das SecureMail Portal der TUD https://securemail.tu-dresden.de in einem PDF–Dokument an zih@tu-dresden.de bzw. an: TU Dresden, ZIH, Herrn Prof. Dr. Wolfgang E. Nagel, Helmholtzstr. 10, 01069 Dresden. Ihre Bewerbungsunterlagen werden nicht zurückgesandt, bitte reichen Sie nur Kopien ein. Vorstellungskosten werden nicht übernommen.
Hinweis zum Datenschutz: Welche Rechte Sie haben und zu welchem Zweck Ihre Daten verarbeitet werden sowie weitere Informationen zum Datenschutz haben wir auf der Webseite https://tu-dresden.de/karriere/datenschutzhinweis für Sie zur Verfügung gestellt.
]]>An der Fakultät Wirtschaftswissenschaften ist an der Professur für Betriebswirtschaftslehre, insbesondere Betriebliches Rechnungswesen/Controlling zum nächstmöglichen Zeitpunkt eine Stelle als
wiss. Mitarbeiter:in / Doktorand:in (m/w/d)
(bei Vorliegen der persönlichen Voraussetzungen E 13 TV-L)
für 3 Jahre mit Verlängerungsmöglichkeit (Beschäftigungsdauer gemäß WissZeitVG), mit 75% der regelmäßigen wöchentlichen Arbeitszeit und dem Ziel der eigenen wiss. Weiterqualifikation (i.d.R. Promotion), zu besetzen. Eine aufgabenspezifische Aufstockung der regelmäßigen wöchentlichen Arbeitszeit ist im vorgegebenen rechtlichen Rahmen möglich.
Aufgaben:
Voraussetzungen:
Wir bieten:
Die TUD strebt eine Erhöhung des Anteils von Frauen an und bittet diese deshalb ausdrücklich um deren Bewerbung. Die Universität ist eine zertifizierte familiengerechte Hochschule und verfügt über einen Dual Career Service. Bewerbungen schwerbehinderter Menschen sind besonders willkommen. Bei gleicher Eignung werden diese oder ihnen Kraft SGB IX von Gesetzes wegen Gleichgestellte bevorzugt eingestellt.
Ihre aussagekräftige Bewerbung senden Sie bitte mit den üblichen Unterlagen bis zum 11.04.2024 (es gilt der Poststempel der Zentralen Poststelle bzw. der Zeitstempel auf dem E-Mail-Server der TUD) bevorzugt über das SecureMail Portal der TUD https://securemail.tu-dresden.de in einem PDF-Dokument an lehrstuhl.controlling@mailbox.tu-dresden.de bzw. an: TU Dresden, Fakultät Wirtschaftswissenschaften, Professur für Betriebswirtschaftslehre, insbesondere Betriebliches Rechnungswesen/Controlling, Herrn Prof. Dr. rer. pol. habil. Thomas Günther, Helmholtzstr. 10, 01069 Dresden. Ihre Bewerbungsunterlagen werden nicht zurückgesandt, bitte reichen Sie nur Kopien ein. Vorstellungskosten werden nicht übernommen.
Hinweis zum Datenschutz: Welche Rechte Sie haben und zu welchem Zweck Ihre Daten verarbeitet werden sowie weitere Informationen zum Datenschutz haben wir auf der Webseite https://tu-dresden.de/karriere/datenschutzhinweis für Sie zur Verfügung gestellt.
]]>15 Doctoral Researchers in Food Systems Economics
(all genders welcome)
to join the Research Training Group (RTG) 2654 “Sustainable Food Systems” funded by the German Research Foundation (DFG).
The positions should be filled by 1 September 2024. The regular working hours will be 65% (currently 25.87 hours per week) with a limited contract of three years to 31 August 2027. The salary is in accordance with the German public service salary scale E13 TVL (65%). These are qualification positions for junior researchers pursuing a PhD degree.
The positions involve interdisciplinary research on questions related to “Sustainable Food Systems”. Food and agriculture are playing key roles for many of the global challenges such as poverty, undernutrition, obesity, climate change, and biodiversity loss. It is obvious that the United Nations’ Sustainable Development Goals (SDGs) cannot be achieved without major changes in food production, distribution, and consumption. But what types of changes are useful and how these changes can be implemented politically, economically, and socially are open questions that will be addressed in the RTG, focusing on both rich and poor countries. The Program is implemented in cooperation with the International Food Policy Research Institute (IFPRI) in Washington DC and KU Leuven in Belgium. The positions are based in Göttingen (Germany), but will require international travel for data collection and exchange with collaborators.
Successful candidates will have an outstanding Master’s degree (or equivalent) in food and agricultural economics, development economics, general economics, sustainability studies, (food) marketing, or related social sciences disciplines, strong analytical skills, experience with relevant statistical methods, proven interest in topics related to sustainable food systems, strong computer skills, and excellent command of the English language. We also expect successful candidates to be active team players in the RTG. Experience with data collection in an international context will be a plus. As part of our work-life-balance strategy, financial support for childcare costs during travel is possible.
The University of Göttingen is an equal opportunities employer and places particular emphasis on fostering career opportunities for women. Qualified women are therefore strongly encouraged to apply in fields in which they are underrepresented. The University has committed itself to being a family-friendly institution and supports their employees in balancing work and family life. The mission of the University is to employ a greater number of severely disabled persons. Applications from severely disabled persons with equivalent qualifications will be given preference.
Please submit your application until 20 March 2024. Further details about the RTG and more information regarding the application process and material can be found on our website (www.uni-goettingen.de/sustainablefood).
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Welche Voraussetzungen sollten Sie mitbringen?
Ein abgeschlossenes, wissenschaftliches Hochschulstudium der Elektrotechnik, des Wirtschaftsingenieurwesens Elektrotechnik oder eines vergleichbaren naturwissenschaftlich-technischen Studienganges ist zwingend erforderlich für die Einstellung als wissenschaftliche*r. Mitarbeiter*in.
Folgende Fähigkeiten / Kenntnisse sind für potentielle Mitarbeiter*innen sehr hilfreich:
- Grundkenntnisse in der Systemauslegung mittels Model-Based Systems Engineering
- Vorkenntnisse im Bereich von HGÜ-Komponenten und -Netzen
- Grundkenntnisse mit Programmierumgebungen (SysML, PSCAD, MATLAB/Simulink)
- Teamfähigkeit und berufliches wie soziales Engagement
- Gute Deutsch- und Englischkenntnisse in Wort und Schrift
Technische Universität Braunschweig
elenia Institut für Hochspannungstechnik und Energiesysteme
Was bieten wir?
- Die Möglichkeit zur Promotion
- Eigenständig organisierbares Arbeiten in einem dynamischen, jungen Team
- Die Möglichkeit zur aktiven Zusammenarbeit mit Partnern und Kollegen aus europäischen Forschungsprojekten und -bereichen
- Sowohl die Möglichkeit zur Arbeit im Labor als auch zur rechnergestützten Synthese und Analyse von Systemen und Komponenten
- Eine enge Mitarbeiterbetreuung sowie ein breit gefächertes Angebot an außerfachlichen Aktivitäten
Die Bezahlung erfolgt je nach Aufgabenübertragung und Erfüllung der persönlichen Voraussetzungen bis EG 13 TV-L. Die Stelle ist grundsätzlich teilzeitgeeignet, sollte jedoch zu 100 Prozent besetzt sein.
Nähere Informationen unter der Durchwahl: +49 (0) 531 - 391 9725
Schwerbehinderte werden bei gleicher Eignung bevorzugt. Ein Nachweis ist beizufügen. Die Bewerbungen von Menschen aller Nationalitäten sind willkommen.
Die TU Braunschweig strebt in allen Bereichen und Positionen an, eine Unterrepräsentanz i.S. des NGG abzubauen. Daher sind Bewerbungen von Frauen besonders erwünscht.
Bewerbungskosten können nicht erstattet werden. Bitte haben Sie Verständnis dafür, dass nicht berücksichtigte Bewerbungen nur gegen einen adressierten und ausreichend frankierten Rück-umschlag zurückgesandt werden können.
Für die Durchführung des Bewerbungsverfahrens speichern wir personenbezogene Daten. Durch Zusendung Ihrer Bewerbung erklären Sie sich damit einverstanden, dass Ihre Daten zu Bewerbungszwecken unter Beachtung der Datenschutzvorschriften elektronisch gespeichert und verarbeitet werden. Weitere Informationen zum Datenschutz entnehmen Sie bitte unserer Datenschutzerklärung unter https://www.tu-braunschweig.de/datenschutzerklaerung-bewerbungen.
Bitte richten Sie Ihre schriftliche Bewerbung mit aussagekräftigen Unterlagen und dem von Ihnen angestrebten Einstellungstermin per Mail an elenia@tu-braunschweig.de oder per Brief an: Geschäftsstelle (z.H. P. Vieth), Technische Universität Braunschweig, elenia Institut für Hochspannungstechnik und Energiesysteme, Schleinitzstr. 23, 38106 Braunschweig.
Bewerbungen können bis zum 05.04.2024 eingereicht werden.
Für erste Informationen nutzen Sie unseren Internetauftritt unter: www.tu-braunschweig.de/elenia.
Wir freuen uns auf Ihre Bewerbung!
PhD Student in Microfluidics and Acoustic Control
Remuneration Group 13 | Limited: 3 years | Starting date: earliest possible | ID: FSDO006/2024 | Deadline: 28.03.2024 | Full-time/Part-time
DESY, with more than 3000 employees at its two locations in Hamburg and Zeuthen, is one of the world's leading research centres. Its research focuses on decoding the structure and function of matter, from the smallest particles of the universe to the building blocks of life. In this way, DESY contributes to solving the major questions and urgent challenges facing science, society and industry. With its ultramodern research infrastructure, its interdisciplinary research platforms and its international networks, DESY offers a highly attractive working environment in the fields of science, technology and administration as well as for the education of highly qualified young scientists.
With significant progress in the time-resolved 3D structure determination of biological molecules in crystals, there is a growing need in developing efficient, simple, compact, and user-friendly devices for delivering microcrystals for the growing field of serial X-ray crystallography. This PhD project aims to develop novel concepts to sense and control the motion of protein microcrystals for improved X‑ray measurements, by combining microfluidic, acoustic, and optical systems. The project will make use of 3D printing by two‑photon stereolithography to rapidly prototype and develop devices that integrate with sample delivery systems.
About your role:
About you:
Good reasons to join:
Look forward to a unique working environment on our international research campus. Respectful cooperation and the well-being of our DESY employees are particularly important to us. Gender equality is an important aspect for us. To support work-life balance we offer flexible working hours, variable part-time, job-sharing models and participation in mobile work (up to 50 %). You will benefit from our family-friendly and collegial atmosphere, our established health management and occupational pension provision. As a public funded employer, we offer you a secure workplace and facilitate your individual career with our comprehensive training and development opportunities. Remuneration is according to the regulations of the TV‑AVH. DESY offers its employees a financial supplement for a German job ticket at both locations.
For further information please contact Prof. Dr. Dr. Henry Chapman +49 40 8998‑4155 (Henry.Chapman@desy.de).
DESY in Hamburg does not grant doctoral degrees directly but collaborates with the University of Hamburg. Candidates for thesis research will have to satisfy the terms of admission for doctoral theses of the University of Hamburg. PhD students receive a monthly salary of 67 % of the payment of the remuneration group 13 TVöD (Federal Government).
Please submit your complete application documents (letter of motivation, CV, relevant certificates and two letters of references) via our application portal. Please use our online tool for the submission of the letters of reference: Additional application documents
We look forward to receiving your application via our application portal:
DESY promotes equal opportunities and diversity. The professional development of women is very important to us and therefore we strongly encourage women to apply for the vacant position.
Applications from severely disabled persons will be given preference if they are equally qualified (sbv.desy.de).
You can find further information here:
https://www.desy.de/career
Deutsches Elektronen-Synchrotron DESY
Human Resources Department | Notkestraße 85 | 22607 Hamburg
Phone: +49 40 8998-3392
The Faculty of Electrical and Computer Engineering, Institute of Communications Engineering, the Junior Professorship for Quantum Communication Networks offers a position as
Research Associate (m/f/x)
(subject to personal qualification employees are remunerated according to salary group E 13 TV-L)
starting as soon as possible. The position is limited until February 28, 2027. The period of employment is governed by the Fixed Term Research Contracts Act (Wissenschaftszeitvertragsgesetz – WissZeitVG). The position offers the chance to obtain further academic qualification (usually PhD).
Tasks: We are inviting applications for a Research Associate position to contribute to the setup and maintenance of quantum computing and communication platforms and the development of specific user interfaces for research and educational purposes. These position offers the unique opportunity for successful candidates to pursue a Ph.D. throughout the duration of the project. We are looking for highly motivated individuals who excel in teamwork and are passionate about advancing the field of quantum technologies.
Responsibilities: Quantum Computing and Communication User Interfaces
Requirements:
Additional Information:
TUD strives to employ more women in academia and research. We therefore expressly encourage women to apply. The University is a certified family-friendly university and offers a Dual Career Service. We welcome applications from candidates with disabilities. If multiple candidates prove to be equally qualified, those with disabilities or with equivalent status pursuant to the German Social Code IX (SGB IX) will receive priority for employment.
Please submit your detailed application with the usual documents by April 2, 2024 (stamped arrival date of the university central mail service or the time stamp on the email server of TUD applies), preferably via the TUD SecureMail Portal https://securemail.tu-dresden.de by sending it as a single pdf file to kseniia.lemesheva@tu-dresden.de or to: TU Dresden, Fakultät Elektrotechnik und Informationstechnik, Institut für Nachrichtentechnik, Juniorprofessur für Quantenkommunikationssnetze, Herrn Prof. Dr.-Ing. Riccardo Bassoli, Helmholtzstr. 10, 01069 Dresden, Germany. Please submit copies only, as your application will not be returned to you. Expenses incurred in attending interviews cannot be reimbursed.
Reference to data protection: Your data protection rights, the purpose for which your data will be processed, as well as further information about data protection is available to you on the website: https://tu-dresden.de/karriere/datenschutzhinweis.
]]>The Faculty of Electrical and Computer Engineering, Institute of Communications Engineering, the Junior Professorship for Quantum Communication Networks offers a position as
Research Associate (m/f/x)
(subject to personal qualification employees are remunerated according to salary group E 13 TV-L)
starting as soon as possible. The position is limited until February 28, 2027. The period of employment is governed by the Fixed Term Research Contracts Act (Wissenschaftszeitvertragsgesetz – WissZeitVG). The position offers the chance to obtain further academic qualification (usually PhD).
Tasks: We are inviting applications for a Research Associate position to contribute to the setup and maintenance of quantum computing and communication platforms and the development of specific user interfaces for research and educational purposes. These position offers the unique opportunity for successful candidates to pursue a Ph.D. throughout the duration of the project. We are looking for highly motivated individuals who excel in teamwork and are passionate about advancing the field of quantum technologies.
Responsibilities: Quantum Computing Algorithms
Requirements:
Additional Information:
TUD strives to employ more women in academia and research. We therefore expressly encourage women to apply. The University is a certified family-friendly university and offers a Dual Career Service. We welcome applications from candidates with disabilities. If multiple candidates prove to be equally qualified, those with disabilities or with equivalent status pursuant to the German Social Code IX (SGB IX) will receive priority for employment.
Please submit your detailed application with the usual documents by April 2, 2024 (stamped arrival date of the university central mail service or the time stamp on the email server of TUD applies), preferably via the TUD SecureMail Portal https://securemail.tu-dresden.de by sending it as a single pdf file to kseniia.lemesheva@tu-dresden.de or to: TU Dresden, Fakultät Elektrotechnik und Informationstechnik, Institut für Nachrichtentechnik, Juniorprofessur für Quantenkommunikationsnetze, Herrn Prof. Dr.-Ing. Riccardo Bassoli, Helmholtzstr. 10, 01069 Dresden, Germany. Please submit copies only, as your application will not be returned to you. Expenses incurred in attending interviews cannot be reimbursed.
Reference to data protection: Your data protection rights, the purpose for which your data will be processed, as well as further information about data protection is available to you on the website: https://tu-dresden.de/karriere/datenschutzhinweis.
]]>The Faculty of Electrical and Computer Engineering, Institute of Communications Engineering, the Junior Professorship for Quantum Communication Networks offers a position as
Research Associate (m/f/x)
(subject to personal qualification employees are remunerated according to salary group E 13 TV-L)
starting as soon as possible. The position is limited until February 28, 2027. The period of employment is governed by the Fixed Term Research Contracts Act (Wissenschaftszeitvertragsgesetz – WissZeitVG). The position offers the chance to obtain further academic qualification (usually PhD).
Tasks: We are inviting applications for a Research Associate position to contribute to the setup and maintenance of quantum computing and communication platforms and the development of specific user interfaces for research and educational purposes. These position offers the unique opportunity for successful candidates to pursue a Ph.D. throughout the duration of the project. We are looking for highly motivated individuals who excel in teamwork and are passionate about advancing the field of quantum technologies.
Responsibilities: Quantum Computing and Communication Research
Requirements:
Additional Information:
TUD strives to employ more women in academia and research. We therefore expressly encourage women to apply. The University is a certified family-friendly university and offers a Dual Career Service. We welcome applications from candidates with disabilities. If multiple candidates prove to be equally qualified, those with disabilities or with equivalent status pursuant to the German Social Code IX (SGB IX) will receive priority for employment.
Please submit your detailed application with the usual documents by April 2, 2024 (stamped arrival date of the university central mail service or the time stamp on the email server of TUD applies), preferably via the TUD SecureMail Portal https://securemail.tu-dresden.de by sending it as a single pdf file to kseniia.lemesheva@tu-dresden.de or to: TU Dresden, Fakultät Elektrotechnik und Informationstechnik, Institut für Nachrichtentechnik, Juniorprofessur für Quantenkommunikationsnetze, Herrn Prof. Dr.-Ing. Riccardo Bassoli, Helmholtzstr. 10, 01069 Dresden, Germany. Please submit copies only, as your application will not be returned to you. Expenses incurred in attending interviews cannot be reimbursed.
Reference to data protection: Your data protection rights, the purpose for which your data will be processed, as well as further information about data protection is available to you on the website: https://tu-dresden.de/karriere/datenschutzhinweis.
]]>At the Faculty of Electrical and Computer Engineering, the Institute of Semiconductors and Microsystems, together with the German Cancer Research Center site Dresden, Division “Smart Technologies for Tumor Therapy”, offers a position as
Research Associate / PhD Student (m/f/x)
(subject to personal qualification employees are remunerated according to salary group E 13 TV-L)
starting as soon as possible. The position is limited until December 31, 2027. The period of employment is governed by the Fixed Term Research Contracts Act (Wissenschaftszeitvertragsgesetz - WissZeitVG). The position aims at obtaining further academic qualification (usually PhD). The project is funded by the European Research Council (ERC) Starting Grant VIBEBOT.
Tasks: The aim of the project is to design, model, fabricate and test a wireless micro-sensor which uses magnetic fields for sensing in biological soft tissues.
Specific tasks for the research include:
Requirements: a university degree equivalent to a Master level in Engineering, Applied Physics or relevant subjects is required. The successful candidate should be self-motivated and possess excellent English skills, also, be open to discuss new ideas in an interdisciplinary team and be flexible to apply various experimental methods. An interest or experience in the fields of mircosystem engineering, microdevices and microfluidics, soft biomaterials characterization and modeling, wireless actuation schemes are preferred.
For further information, please visit the research group’s website (https://www.dkfz.de/en/smart-technologies-tumortherapie/index.php) and contact Prof. Tian Qiu. Feel free to send informal inquiries.
TUD strives to employ more women in academia and research. We therefore expressly encourage women to apply. The University is a certified family-friendly university and offers a Dual Career Service. We welcome applications from candidates with disabilities. If multiple candidates prove to be equally qualified, those with disabilities or with equivalent status pursuant to the German Social Code IX (SGB IX) will receive priority for employment.
Please submit your detailed application with the usual documents by March 28, 2024 (stamped arrival date of the university central mail service or the time stamp on the email server of TUD applies), preferably via the TUD SecureMail Portal https://securemail.tu-dresden.de by sending it as a single PDF file quoting the job-ID “w23-458” to nicole.tuerkowsky@mailbox.tu-dresden.de or to: TU Dresden, Fakultät Elektrotechnik und Informationstechnik, Institut für Halbleiter- und Mikrosystemtechnik, z. Hd. Frau Maria Wache, Helmholtzstr. 10, 01069 Dresden, Germany. Please submit copies only, as your application will not be returned to you. Expenses incurred in attending interviews cannot be reimbursed.
Reference to data protection: Your data protection rights, the purpose for which your data will be processed, as well as further information about data protection is available to you on the website: https://tu-dresden.de/karriere/datenschutzhinweis.
]]>An der Fakultät Maschinenwesen, Institut für Maschinenelemente und Maschinenkonstruktion, ist an der Professur für Technisches Design (Prof. Dr.-Ing. Jens Krzywinski), vorbehaltlich vorhandener Mittel, zum nächstmöglichen Zeitpunkt eine Stelle als
wiss. Mitarbeiter:in (m/w/d) Psychologie/Human Factors/User Experience
(bei Vorliegen der persönlichen Voraussetzungen E 13 TV-L)
für 36 Monate mit der Option auf Verlängerung (Beschäftigungsdauer gem. WissZeitVG), mit 75 % der regelmäßigen wöchentlichen Arbeitszeit innerhalb des Projektes „ReCAicle“, zu besetzen. Es besteht die Gelegenheit zur eigenen wiss. Weiterqualifikation (i. d. R. Promotion).
Im Rahmen des durch den Freistaat Sachsen und den Europäischen Sozialfond (ESF Plus) geförderten Projektvorhabens sollen gemeinsam mit dem Praxispartner ITEXIA GmbH die Grundlagen eines „KI-basierten Conversational Agent (CA) für nachhaltige Verhaltensänderungen in Bezug auf die Nutzung von Assets“ erforscht werden. Perspektivisch soll durch den CA ein signifikanter Beitrag zur Kreislaufwirtschaft geleistet werden, indem dieser Nutzenden wichtige Informationen, Erklärungen und Konsequenzen der Verwendung von Assets transparent vermittelt.
Aufgaben: Erarbeitung von Strategien zur Erhöhung von nachhaltigen Verhaltensweisen z. B. Nudging, Boosting; Vorbereitung und Durchführung von Nutzerstudien z. B. in Form von Prototypenevaluierung; Auswertung qualitativer und quantitativer Daten; Publikation von wiss. Ergebnissen in Konferenzbeiträgen oder Journalartikeln in deutscher und englischer Sprache.
Voraussetzungen: wiss. Hochschulabschluss, bevorzugt in Psychologie, Human Factors, Informatik oder einem angrenzenden Studiengang; erste Erfahrungen in der Studienplanung und ‑durchführung; Kenntnisse im Umgang mit gängiger Auswertungssoftware für quantitative Daten wie SPSS oder Programmiersprachen wie R oder Python; Interesse an KI-gestützten Softwarelösungen und Nachhaltigkeit; Team- und Kommunikationsfähigkeit; gute Deutsch- und Englischkenntnisse. Erwünscht sind Kenntnisse in gängigen UX-Forschungsmethoden, Erfahrungen mit der Erhebung und Auswertung qualitativer Daten sowie Umgang mit gängiger Auswertungssoftware für qualitative Daten wie MAXQDA.
Die TUD strebt eine Erhöhung des Anteils von Frauen an und bittet diese deshalb ausdrücklich um deren Bewerbung. Die Universität ist eine zertifizierte familiengerechte Hochschule und verfügt über einen Dual Career Service. Bewerbungen schwerbehinderter Menschen sind besonders willkommen. Bei gleicher Eignung werden diese oder ihnen Kraft SGB IX von Gesetzes wegen Gleichgestellte bevorzugt eingestellt.
Ihre aussagekräftige Bewerbung senden Sie bitte mit den üblichen Unterlagen bis zum 26.03.2024 (es gilt der Poststempel der Zentralen Poststelle bzw. der Zeitstempel auf dem E-Mail-Server der TUD) an: TU Dresden, Fakultät Maschinenwesen, Institut für Maschinenelemente und Maschinenkonstruktion, Professur für Technisches Design, Herrn Prof. Dr.-Ing. Jens Krzywinski, Helmholtzstr. 10, 01069 Dresden oder über das SecureMail Portal der TUD https://securemail.tu-dresden.de in einem PDF–Dokument an technisches.design@tu-dresden.de. Ihre Bewerbungsunterlagen werden nicht zurückgesandt, bitte reichen Sie nur Kopien ein. Vorstellungskosten werden nicht übernommen.
Hinweis zum Datenschutz: Welche Rechte Sie haben und zu welchem Zweck Ihre Daten verarbeitet werden sowie weitere Informationen zum Datenschutz haben wir auf der Webseite https://tu-dresden.de/karriere/datenschutzhinweis für Sie zur Verfügung gestellt.
]]>An der Fakultät Maschinenwesen, Institut für Strömungsmechanik, ist an der Professur für Turbomaschinen und Flugantriebe zum nächstmöglichen Zeitpunkt eine Stelle als
wiss. Mitarbeiter:in / Doktorand:in (m/w/d)
(bei Vorliegen der persönlichen Voraussetzungen E 13 TV-L)
für 36 Monate mit der Option auf Verlängerung (Beschäftigungsdauer gem. WissZeitVG) u. dem Ziel der eigenen wiss. Weiterqualifikation (i.d.R. Promotion) zu besetzen.
Aufgaben: wiss. Lehr- und Forschungstätigkeiten; Die probabilistische Untersuchung von Flugantrieben und energietechnischen Anlagen ist ein Forschungsschwerpunkt der Professur für Turbomaschinen und Flugantriebe. Neben probabilistischen Methoden kommen dabei auch verstärkt Methoden der Künstlichen Intelligenz und Data Science zum Einsatz. Sie entwickeln bestehende Methoden eigenständig weiter und erweitern sie auf neue Anwendungsfälle. Darüber hinaus erschließen Sie neue Anwendungsfelder des maschinellen Lernens auf dem Gebiet der Flugantriebe und initiieren durch Ihre Arbeit Technologieprojekte mit Industriepartnern. Ihre Ergebnisse präsentieren Sie sowohl intern als auch extern in Form von wiss. Publikationen und auf internationalen Konferenzen.
Voraussetzungen: überdurchschnittlicher wiss. Hochschulabschluss in den Ingenieurwissenschaften, möglichst mit Schwerpunkt Turbomaschinen oder Luft- und Raumfahrttechnik; strukturierte und eigenverantwortliche analytische Arbeitsweise; hohes Maß an Qualitätsbewusstsein und Teamorientierung; Sprachkenntnisse: Deutsch und Englisch, sehr gute Kenntnisse in Wort und Schrift. Programmierkenntnisse, idealerweise in Python und den gängigen Modulen (z. B. NumPy, scikit-learn, TensorFlow, PyTorch) sind von Vorteil, ebenso Erfahrungen mit numerischen Methoden in der Entwicklung und Analyse von Turbomaschinen.
Die TUD strebt eine Erhöhung des Anteils von Frauen an und bittet diese deshalb ausdrücklich um deren Bewerbung. Die Universität ist eine zertifizierte familiengerechte Hochschule und verfügt über einen Dual Career Service. Bewerbungen schwerbehinderter Menschen sind besonders willkommen. Bei gleicher Eignung werden diese oder ihnen Kraft SGB IX von Gesetzes wegen Gleichgestellte bevorzugt eingestellt.
Ihre aussagekräftige Bewerbung senden Sie bitte mit den üblichen Unterlagen (Anschreiben mit Forschungsinteressen, Lebenslauf, Zeugnisse, Referenzen) unter dem Stichwort „Probabilistik“ bis zum 28.03.2024 (es gilt der Poststempel der Zentralen Poststelle bzw. der Zeitstempel auf dem E-Mail-Server der TUD) an: TU Dresden, Fakultät Maschinenwesen, Institut für Strömungsmechanik, Professur für Turbomaschinen und Flugantriebe, Herrn Prof. Dr.-Ing. habil. Ronald Mailach, Helmholtzstr. 10, 01069 Dresden oder über das SecureMail Portal der TUD https://securemail.tu-dresden.de in einem PDF-Dokument an sekretariat-tfa@tu-dresden.de. Ihre Bewerbungsunterlagen werden nicht zurückgesandt, bitte reichen Sie nur Kopien ein. Vorstellungskosten werden nicht übernommen.
Hinweis zum Datenschutz: Welche Rechte Sie haben und zu welchem Zweck Ihre Daten verarbeitet werden sowie weitere Informationen zum Datenschutz haben wir auf der Webseite https://tu-dresden.de/karriere/datenschutzhinweis für Sie zur Verfügung gestellt.
]]>
Ihre Aufgaben:
Im Rahmen des europäischen HORIZON-Projekts SUSTEPS wird am IEK-14 ein Verfahren entwickelt, mit dem leichte Kohlenwasserstoffe aus der Destillation und der hydrothermalen Verflüssigung zurückgewonnen werden können, indem sie durch Reformierung und Wassergas-Shift-Reaktion in ein wasserstoffreiches Synthesegas umgewandelt werden, das zur Veredelung in der Bioraffinerie verwendet wird. Zudem zeigen Prozessanalysen im Rahmen von Power-to-Fuel-Verfahren am IEK-14 das große Potenzial einer Umwandlung der nicht rückführbaren Nebenprodukte einer Kraftstoffsynthese zur Veredelung zu einem Synthesegas in einem Reformer. In diesem Zusammenhang liegt der Schwerpunkt der Dissertation auf der Entwicklung und Erprobung von Reformierungskonzepten zur Veredelung von Nebenprodukten zur Herstellung von nachhaltigen Kraftstoffen. Ihre Aufgaben umfassen unter anderem:
Ihr Profil:
Auch wenn Sie sich nicht zu 100% in dieser Stellenausschreibung wiederfinden, freuen wir uns über Ihre Bewerbung. Wir möchten, dass Sie als Person zu uns passen, nicht nur Ihr Profil.
Unser Angebot:
Wir arbeiten an hochaktuellen gesellschaftlich relevanten Themen und bieten Ihnen die Möglichkeit, den Wandel aktiv mitzugestalten! Wir unterstützen Sie in Ihrer Arbeit durch:
Neben spannenden Aufgaben und einem kollegialen Miteinander bieten wir Ihnen noch viel mehr: https://go.fzj.de/Benefits.
Die Position ist auf drei Jahre befristet. Die Vergütung erfolgt analog der Entgeltgruppe 13 (75%) des Tarifvertrags für den öffentlichen Dienst (TVöD-Bund) zuzüglich 60% eines Monatsgehaltes als Sonderzahlung („Weihnachtsgeld“). Informationen zur Promotion im Forschungszentrum Jülich inklusive der Standorte finden Sie hier: https://go.fzj.de/Promotion.
Wir freuen uns über Bewerbungen von Menschen mit vielfältigen Hintergründen, z.B. hinsichtlich Alter, Geschlecht, Behinderung, sexueller Orientierung / Identität sowie sozialer, ethnischer und religiöser Herkunft. Ein chancengerechtes, diverses und inklusives Arbeitsumfeld, in dem alle ihre Potenziale verwirklichen können, ist uns wichtig.
Wir freuen uns auf Ihre Bewerbung. Die Position ist bis zur erfolgreichen Besetzung ausgeschrieben. Bitte bewerben Sie sich daher möglichst zeitnah über unser Online-Bewerbungsportal.
Fragen zur Ausschreibung?
Kontaktieren Sie uns gerne über unser Kontaktformular. Bitte beachten Sie, dass aus technischen Gründen keine Bewerbungen per E-Mail angenommen werden können.
# 6 DER BESTEN ARBEITGEBER 2023 AUF GLASSDOOR
]]>The research group Microbiota-Associated Natural Products is focusing on the identification, isolation, characterization, and study of specific RiPP natural products produced from commensal or pathogenic bacteria. We are especially interested in new bioactive compounds with antimicrobial properties that can be used as potential drug leads for the development of novel anti-infectives and elucidating their roles in their native environments.
This project revolves around the investigation and optimization of the stability and antimicrobial properties of natural products belonging to the class of lasso peptides. In addition, bioengineering strategies will be employed to install new functionalities in these lasso peptide scaffolds and to generate conjugates with other antimicrobial molecules. The goals of this research project are to perform structure-activity-relationship (SAR) studies on the compounds and improving their stability under physiological conditions to enhance their potential for the development of novel therapeutics. This project will be carried out in collaboration with the laboratory of Prof. John Chu from the National Taiwan University. Joint meetings with the collaboration partners are planned to take place both in Germany and in Taiwan on an alternating basis.
Responsibilities:
Requirements:
Advantageous for this position:
We offer you:
People with severe disabilities and equivalent professional qualifications who are suitable for the position are given preference. The HZI strives for professional equality between women and men. The position is suitable for part-time work.
Starting date: as soon as possible. The contract will initially run for three years.
Salary: analogue to E13 TVöD Bund (55%)
Working time: 19.5 hours per week
Place of work: Saarbrücken/ HIPS
Probation period: 6 months
Application: Applicants are required to complete the online application form here:
https://hzi.opencampus.net/ (Please select Job No. 197/2023).
For further information please contact Dr. Julian Hegemann directly via email: julian.hegemann@helmholtz-hips.de.
Further information about the institute and the research group can be found on our website: https://www.helmholtz-hips.de/en/research/teams/team/microbiota-associated-natural-products/
]]>Verstärken Sie diesen Bereich zum nächstmöglichen Zeitpunkt als
Doktorand – Mehrskalige tomographische Analyse von porösen Katalysatoren für Wasserstoffanwendungen (w/m/d)
Ihre Aufgaben:
Sie unterstützen mit Ihren Ideen und Ihrer Arbeit die Abteilung Elektrokatalytische Grenzflächenverfahrenstechnik, geleitet von Prof. Simon Thiele, im Team Kompositmembrananalyse und -design, geleitet von Dr. Thomas Böhm. Die Abteilung fokussiert sich auf die Herstellung, Analyse und Simulation funktional optimaler Strukturen in elektrochemischen Systemen von der Nanometerskala bis zur Mikrometerskala mit einem Fokus auf die tomographische Analyse von porösen Materialien. Ihre Aufgaben im Detail:
Ihr Profil:
Wir suchen Wissenschaftler (w/m/d), die perfekt zu uns passen: Expertise, Teamfähigkeit, Auffassungsgabe und ein harmonisches Arbeitsklima sind für uns eine untrennbare Kombination.
Unser Angebot:
Wir arbeiten an hochaktuellen gesellschaftlich relevanten Themen und bieten Ihnen die Möglichkeit, den Wandel aktiv mitzugestalten! Wir unterstützen Sie in Ihrer Arbeit durch:
Die Position ist auf drei Jahre befristet. Die Vergütung erfolgt analog der Entgeltgruppe 13 (75%) des Tarifvertrags für den öffentlichen Dienst (TVöD-Bund) zuzüglich 60% eines Monatsgehaltes als Sonderzahlung („Weihnachtsgeld“).
Dienstort: Erlangen
Wir freuen uns über Bewerbungen von Menschen mit vielfältigen Hintergründen, z.B. hinsichtlich Alter, Geschlecht, Behinderung, sexueller Orientierung / Identität sowie sozialer, ethnischer und religiöser Herkunft. Ein chancengerechtes, diverses und inklusives Arbeitsumfeld, in dem alle ihre Potenziale verwirklichen können, ist uns wichtig.
Wir freuen uns auf Ihre Bewerbung. Die Position ist bis zur erfolgreichen Besetzung ausgeschrieben. Bitte bewerben Sie sich daher möglichst zeitnah über unser Online-Bewerbungsportal.
Fragen zur Ausschreibung?
Kontaktieren Sie uns gerne über unser Kontaktformular. Bitte beachten Sie, dass aus technischen Gründen keine Bewerbungen per E-Mail angenommen werden können.
For more information, please visit: www.isct.uni-tuebingen.de/wsic/
If you have any questions, please contact Dr. Fabian Schmidt, office.wsic@med.uni-tuebingen.de, Tel. +49 7071 2987161
Application Deadline: 18.01.2024
Please upload your application and documents to our recruiting portal (job offer number is 3666):
https://jobs.medizin.uni-tuebingen.de/Job/3666/PhD-Student-(f-m-d)
Universitätsklinikum Tübingen
Radiologische Klinik
Präklinische Bildgebung und Radiopharmazie Office WSIC
Röntgenweg 13
72076 Tübingen
office.wsic@med.uni-tuebingen.de
Ihre Aufgaben:
Sie werden in unserem Forschungsteam, dem Simulation and Data Lab Quantum Materials, Spitzenforschung betreiben, um eine wissenschaftliche Software (libNEGF) zu erweitern, die zur Simulation des Quantentransports in nanoelektronischen Geräten verwendet wird. Sie werden Teil eines paneuropäischen Kompetenzzentrums (EoCoE) sein, mit dem ultimativen Ziel, groß angelegte „in silico“-Simulationen mit Anwendung auf Energieerzeugung und -transport voranzutreiben. Sie werden eine Schlüsselrolle einnehmen bei der Verbesserung der Skalierbarkeit des Codes auf europäischen Prä-Exascale- und zukünftigen Exascale-Systemen (LUMI, LEONARDO, JUPITER usw.) sowie bei der Implementierung neuartiger paralleler Algorithmen und der Sicherstellung der Gesamtskalierbarkeit des Codes. Ihre Aufgaben umfassen die Algorithmenentwicklung, die parallele Programmierung für verteilte CPU- und Multi-GPU-Architekturen und den Aufbau einer effizienten Schnittstelle, die Algorithmen mit der Implementierung und letztendlich den Computerarchitekturen verbindet. Sie werden:
Ihr Profil:
Wir suchen einen hoch motivierten Forscher (w/m/d), der sich für neue wissenschaftliche Vorhaben mit interdisziplinären Ansätzen begeistert. Dafür haben Sie:
Unser Angebot:
Wir arbeiten an hochaktuellen gesellschaftlich relevanten Themen und bieten Ihnen die Möglichkeit, den Wandel aktiv mitzugestalten. Sie erwartet ein vielseitiges Angebot:
Neben spannenden Aufgaben und einem kollegialen Miteinander bieten wir Ihnen noch viel mehr: https://go.fzj.de/Benefits.
Die Position ist zunächst auf drei Jahre befristet mit der Möglichkeit einer längerfristigen Perspektive. Die Vergütung erfolgt analog der Entgeltgruppe 13 (75%) des Tarifvertrags für den öffentlichen Dienst (TVöD-Bund) zuzüglich 60% eines Monatsgehaltes als Sonderzahlung („Weihnachtsgeld“). Informationen zur Promotion im Forschungszentrum Jülich inklusive der Standorte finden Sie hier: https://go.fzj.de/Promotion.
Wir freuen uns auf Ihre Bewerbung. Die Position ist bis zur erfolgreichen Besetzung ausgeschrieben. Bitte bewerben Sie sich daher möglichst zeitnah über unser Online-Bewerbungsportal.
Fragen zur Ausschreibung?
Kontaktieren Sie uns gerne über unser Kontaktformular. Bitte beachten Sie, dass aus technischen Gründen keine Bewerbungen per E-Mail angenommen werden können.
]]>Elektrochemische Energiewandler sind ein integraler Bestandteil der Energiewende, da mit ihnen elektrische Energie aus erneuerbaren Ressourcen gespeichert und bei Bedarf wieder zur Verfügung gestellt werden kann. Um die Effizienz und Zuverlässigkeit dieser Energiewandler zu optimieren, untersuchen wir im Institut für Energie- und Klimaforschung – Elektrochemische Verfahrenstechnik (IEK-14) – die grundlegenden Eigenschaften von Elektrolyseuren mit elektrochemischen, spektroskopischen und mikroskopischen Methoden. Hier erhalten Sie weiterführende Informationen zu unserer Mission und unseren Projekten: go.fzj.de/pcl.
Verstärken Sie diesen Bereich zum nächstmöglichen Zeitpunkt als
Doktorand – Stabile Katalysatoren für die PEM-Elektrolyse (w/m/d)
Ihre Aufgaben:
PEM-Elektrolyseure sind vielversprechende Energiewandler, um Wasserstoff mit Energie aus Wind- und Solaranlagen zu erzeugen, da sie besonders schnell auf Netzschwankungen reagieren können. Um langlebige Elektrolyseure zu entwickeln, werden insbesondere stabile Katalysatoren für die Wasserspaltung benötigt. In einem deutsch-koreanischen Kooperationsprojekt soll daher das Alterungsverhalten von Elektroden in PEM-Elektrolyseuren untersucht werden. Im Einzelnen umfassen Ihre Aufgaben:
Ihr Profil:
Unser Angebot:
Wir arbeiten an hochaktuellen gesellschaftlich relevanten Themen und bieten Ihnen die Möglichkeit, den Wandel aktiv mitzugestalten. Sie erwartet ein vielseitiges Angebot:
Neben spannenden Aufgaben und einem kollegialen Miteinander bieten wir Ihnen noch viel mehr: https://go.fzj.de/Benefits.
Die Stelle ist auf drei Jahre befristet. Die Vergütung erfolgt analog der Entgeltgruppe 13 (75%) des Tarifvertrags für den öffentlichen Dienst (TVöD-Bund) zuzüglich 60% eines Monatsgehaltes als Sonderzahlung („Weihnachtsgeld“). Informationen zur Promotion im Forschungszentrum Jülich inklusive der Standorte finden Sie hier: https://go.fzj.de/Promotion.
Wir freuen uns über Bewerbungen von Menschen mit vielfältigen Hintergründen, z.B. hinsichtlich Alter, Geschlecht, Behinderung, sexueller Orientierung / Identität sowie sozialer, ethnischer und religiöser Herkunft. Ein chancengerechtes, diverses und inklusives Arbeitsumfeld, in dem alle ihre Potenziale verwirklichen können, ist uns wichtig.
Wir freuen uns auf Ihre Bewerbung. Die Position ist bis zur erfolgreichen Besetzung ausgeschrieben. Bitte bewerben Sie sich daher möglichst zeitnah über unser Online-Bewerbungsportal.
Fragen zur Ausschreibung?
Kontaktieren Sie uns gerne über unser Kontaktformular. Bitte beachten Sie, dass aus technischen Gründen keine Bewerbungen per E-Mail angenommen werden können.
# 6 DER BESTEN ARBEITGEBER 2023 AUF GLASSDOOR
]]>We are offering a
PhD Position – CO2 Electrolysis and Real-Time Mass Spectrometry Monitoring
Your Job:
Organic electrosynthesis has recently emerged as a powerful application for future sustainable chemical processes. Its selectivity and efficiency, however, rely on developing dedicated catalytic materials. Due to the poor time resolution of offline analytical methods, conventional trial-and-error experiments are generally non-informative concerning monitoring electrode process transients and thus inapplicable for high-throughput experimentations essential for the complexity of reaction parameters to be optimized. You will be part of a team to advance and utilize a unique platform for online real-time analysis employing mass spectrometry for the investigation of selective and efficient chemical CO2 utilization in electrochemical processes.
Your Profile:
Our Offer:
We work on the very latest issues that impact our society and are offering you the chance to actively help in shaping the change! We offer ideal conditions for you to complete your doctoral degree:
The position is for a fixed term of three years. Pay is in line with 75% of pay group 13 of the Collective Agreement for the Public Service (TVöD-Bund) and additionally 60% of a monthly salary as special payment (“Christmas bonus”).
Place of employment: Erlangen
We particularly welcome applications from people from a diverse range of backgrounds (e.g. regardless of age, gender, disabilities, sexual orientation / identity, as well as social, ethnic, and religious background). We strive to offer a diverse and inclusive working environment in which people enjoy equal opportunities and are able to fulfill their potential.
We look forward to receiving your application. The job will be advertised until the position has been successfully filled. You should therefore submit your application as soon as possible via our Online Recruitment System.
Questions about the vacancy?
Please feel free to contact us via our contact form. Please note that for technical reasons we cannot accept applications via e-mail.
At the Institute of Energy and Climate Research – Energy Systems Engineering (IEK-10) –, we focus on the development of models and algorithms for simulation and optimization of decentralized, integrated energy systems. Such systems are characterized by high shares of renewable energies and increasing sector coupling, which leads to high spatial and temporal variability of energy supply and demand as well as a high degree of interdependence of material and energy flows. Our research at the IEK-10 aims to provide scalable and faster-than-real-time capable methods and tools that enable the energy-optimal, cost-efficient, and safe design and operation of future energy systems.
We are offering a
PhD Position – Stochastic Predictive Optimization for the Electrical Grid
Your Job:
In response to the urgent demands posed by climate change in an increasingly global economy and in addition to the goal of reducing dependence on imported energy sources and raw materials, the European energy system is considering a shift from an energy system based on fossil fuels that relies on large power plants to a dynamic, supply- and demand-driven approach, often organized in local energy communities where renewable energy is the main source.
The envisioned system exhibits a level of complexity related to the coordination of distributed renewable resources connected to the electrical grid and the stochastic behavior of consumption and generations, which introduce a high level of uncertainty. To counteract it, optimization methods that can make accurate predictions by compensating for stochastic effects are needed to achieve the goal of sustainability and maintain the stability of the energy system.
We are currently seeking a PhD student for the following research topics:
Your Profile:
Our Offer:
We work on the very latest issues that impact our society and are offering you the chance to actively help in shaping the change. We offer ideal conditions for you to complete your doctoral degree:
The position is for a fixed term of three and a half years, where the first half year serves as orientation and probation period. Pay is in line with 75% of pay group 13 of the Collective Agreement for the Public Service (TVöD-Bund) and additionally 60% of a monthly salary as special payment (“Christmas bonus”). Further information on doctoral degrees at Forschungszentrum Jülich, including our other locations, is available at www.fz-juelich.de/gp/Careers_Docs.
In addition to exciting tasks and a collaborative working atmosphere at Jülich, we have a lot more to offer: https://go.fzj.de/benefits.
We particularly welcome applications from people from a diverse range of backgrounds (e.g. regardless of age, gender, disabilities, sexual orientation / identity, as well as social, ethnic, and religious background). We strive to offer a diverse and inclusive working environment in which people enjoy equal opportunities and are able to fulfill their potential.
We look forward to receiving your application. The job will be advertised until the position has been successfully filled. You should therefore submit your application as soon as possible via our Online Recruitment System!
Questions about the Offer?
Please feel free to contact us via our contact form. Please note that for technical reasons we cannot accept applications via email.
# 6 BEST EMPLOYERS IN GERMANY 2023
]]>wissenschaftliche Mitarbeiter/in "Data Science"
mit dem Ziel einer Promotion zu besetzen.
Das Aufgabengebiet ist die Entwicklung, Implementierung und Evaluation von Methoden und Werkzeugen im Bereich der Datenwissenschaft („Data Science“). Mögliche Forschungsgegenstände sind beispielsweise die Qualität wissenschaftlicher Daten, die Generierung synthetischer Daten oder die Arbeit an der Schnittstelle von Anfrageverarbeitung und Datenschutz. Ihre Arbeit soll aus guter Informatikforschung bestehen, aber auch in Zusammenarbeit mit Anwendern aus anderen Bereichen, wie beispielsweise Energiesystemen, Materialwissenschaften oder Robotik, dort echte Fortschritte ermöglichen. Gern möchten wir Ihnen auch in überschaubarem Umfang Aufgaben in der Lehre übertragen.
Wir erwarten von Ihnen Kenntnisse im Bereich Datenbanken und/oder Datenanalyse sowie grundlegende Programmierkenntnisse oder die Bereitschaft, sich diese rasch anzueignen. Wesentliche Voraussetzungen sind Interesse an wissenschaftlicher Arbeit und ein sehr guter Studienabschluss (Diplom oder Master) in Informatik oder einer verwandten Disziplin wie Mathematik oder Physik. Die Ausschreibung richtet sich auch an Personen, die bereits in der Industrie tätig sind und für ein Dissertationsprojekt an die Universität zurückkehren möchten. Bitte schicken Sie uns Bewerbungsunterlagen, die Ihren Lebenslauf, universitäre Zeugnisse mit Noten und eine kurze Darstellung, warum speziell diese Ausschreibung Sie angesprochen hat, enthalten.
Wir bieten:
Das KIT ist bestrebt, den Anteil an Frauen im wissenschaftlichen Dienst zu erhöhen und begrüßt daher besonders die Bewerbung von Frauen. Schwerbehinderte Bewerber/innen werden bei entsprechender Eignung bevorzugt berücksichtigt.
Ihre Bewerbung senden Sie bitte elektronisch an Herrn Prof. Dr.-Ing. Klemens Böhm,
E-Mail: klemens.boehmatkit.edu, der auch für fachliche Auskünfte gern zur Verfügung steht.
We are offering a
PhD Position – Membrane Electrode Assembly System for CO2 Reduction with Anion Exchange Membrane
Your Job:
The electrocatalytic interface engineering department, led by Prof. Dr.-Ing. Simon Thiele, focuses on manufacturing, analysis, and simulation of functional materials to find an optimum structure on small scales from the micrometer to the nanometer scale. The investigated materials and systems play an essential role in sustainable technologies like water- and CO2-electrolyzers, as well as in fuel cells. Further information about the HI ERN and its research focus can be found on https://www.hi-ern.de! Your tasks regarding the built-up and design of an efficient flow reactor for CO2 electrolysis in detail:
Your Profile:
Our Offer:
We work on the very latest issues that impact our society and are offering you the chance to actively help in shaping the change! We offer ideal conditions for you to complete your doctoral degree:
The position is for a fixed term of three years. Pay is in line with 75% of pay group 13 of the Collective Agreement for the Public Service (TVöD-Bund) and additionally 60% of a monthly salary as special payment (“Christmas bonus”).
Place of employment: Erlangen
We welcome applications from people with diverse backgrounds, e.g., in terms of age, gender, disability, sexual orientation / identity, and social, ethnic, and religious origin. A diverse and inclusive working environment with equal opportunities, in which everyone can realize their potential, is important to us.
We look forward to receiving your application. The job will be advertised until the position has been successfully filled. You should therefore submit your application as soon as possible via our Online Recruitment System!
Questions about the vacancy?
Get in touch with us by using our contact form. Please note that for technical reasons we cannot accept applications via e-mail.
Your Job:
You will be part of the top-class scientific department “Chemical Hydrogen Storage” at the renowned HI ERN. Under the direction of Prof. Dr. Peter Wasserscheid and Dr.-Ing. Michael Geißelbrecht, our department researches and develops a wide range of topics related to chemical hydrogen storage along the entire process chain. In particular, issues in the field of the LOHC technology are addressed across different scales. These topics include the development of tailor-made catalysts, the development and modeling of reactors, and the realization of demonstrators. The department is a world leader in the field of LOHC technology. Become part of this innovative research team!
In a team, you will take part in developing and optimizing catalysts for reactions to release hydrogen from LOHC molecules. In addition to conventional dehydrogenation, this can also be achieved by partial reforming. To research this new approach, you will synthesize and characterize catalysts, which you will then investigate for their activity and selectivity in reaction engineering setups. Through targeted variations of catalyst properties, you will try to derive structure-activity and structure-selectivity relationships and thus obtain customized materials for the reaction. Your tasks in detail:
Your Profile:
Our Offer:
We work on the very latest issues that impact our society and are offering you the chance to actively help in shaping the change! We offer ideal conditions for you to complete your doctoral degree:
The position is for a fixed term of three years. Pay is in line with 75% of pay group 13 of the Collective Agreement for the Public Service (TVöD-Bund) and additionally 60% of a monthly salary as special payment (“Christmas bonus”).
Place of employment: Erlangen
We welcome applications from people with diverse backgrounds, e.g., in terms of age, gender, disability, sexual orientation / identity, and social, ethnic, and religious origin. A diverse and inclusive working environment with equal opportunities, in which everyone can realize their potential, is important to us.
We look forward to receiving your application. The job will be advertised until the position has been successfully filled. You should therefore submit your application as soon as possible via our Online Recruitment System!
Questions about the vacancy?
Get in touch with us by using our contact form. Please note that for technical reasons we cannot accept applications via e-mail.
Your Job:
In pursuit of better energy storage solutions, IEK-9 is researching novel battery systems such as metal-air utilizing environmentally friendly, cheap, abundant materials (e.g. zinc or iron). The leap to practical application of metal-air batteries won’t happen without deep understanding of the degradation processes occurring at different conditions and modes of operation. The failure mechanism of a cell is often manifested by changes in the morphology of active material. However, besides the anode, such a cell consists of electrolyte, cathode (membrane providing oxygen for reaction), current collector, and separator. This makes the whole system more complex. Even a slight change to pH or molarity of the electrolyte might drastically alter its behavior, and – up to now – there is no comprehensive study quantitatively linking the environmental variables (pH, molarity) with observed morphology and electrochemical information. It is caused by practical limitations of typical metallographic techniques, such as destructive, time-consuming sample preparation, and complexity of operando setup. Therefore, imaging techniques such as X-ray computed tomography (XCT), play an important role in providing statistical data necessary to evaluate such a system. XCT is non-destructive, does not require sample preparation, and is able to deliver 3D information in reasonable time if boosted by machine learning (ML). This thesis will be a significant milestone on the way to practical application of metal-air batteries. Observation, via XCT, of the morphology of active material responding in operando to different variables (e.g. pH, molarity) will provide unique insight into the degradation processes taking place. Moreover, acquired imaging data, thanks to its good statistical power, can be used for quantification and to create the universal model incorporating all the variables affecting the performance of the system.
Your tasks will include:
Your Profile:
Our Offer:
We work on the very latest issues that impact our society and are offering you the chance to actively help in shaping the change! We offer ideal conditions for you to complete your doctoral degree:
In addition to exciting tasks and a collaborative working atmosphere at Jülich, we have a lot more to offer: https://go.fzj.de/benefits.
The position is for a fixed term of three years. Pay is in line with 75% of pay group 13 of the Collective Agreement for the Public Service (TVöD-Bund) and additionally 60% of a monthly salary as special payment (“Christmas bonus”). Further information on doctoral degrees at Forschungszentrum Jülich including our other locations is available at https://www.fz-juelich.de/gp/Careers_Docs.
We welcome applications from people with diverse backgrounds, e.g. in terms of age, gender, disability, sexual orientation / identity, and social, ethnic, and religious origin. A diverse and inclusive working environment with equal opportunities in which everyone can realize their potential is important to us.
We look forward to receiving your application. The job will be advertised until the position has been successfully filled. You should therefore submit your application as soon as possible via our Online Recruitment System!
Questions about the Offer?
Please feel free to contact us via our contact form. Please note that for technical reasons we cannot accept applications via email.
# 6 BEST EMPLOYERS IN GERMANY 2023
]]>Job description. This Ph.D. thesis aims at the atomic-scale characterization and bottom-up fabrication of low-dimensional carbon-based nanomaterials with peculiar electronic properties. On-surface synthesis is used to build novel atomically precise graphene nanoribbons and 2D covalently linked carbon-based networks on metal surfaces and 2D materials. The project will use advanced scanning probe techniques, such as scanning tunneling microscopy/spectroscopy (STM/STS) and non-contact atomic force microscopy (nc-AFM) in ultra-high vacuum at low temperatures.
The project is part of the DFG Collaborative Research Center SFB953 – Synthetic carbon allotropes – (https://www.sfb953.research.fau.eu/) and the DFG RTG2861 Planar Carbon Lattices (https://rtg2861-pcl.chm.tu-dresden.de/) that provide close collaboration with research groups from experimental physics, theory, and synthetic chemistry. Collaborators provide specially designed molecular building blocks with tailored functionalities. We offer an outstanding infrastructure with state-of-the-art equipment and broad interdisciplinary environments.
Qualifications. Required qualifications include a master’s degree in Physics, Physical Chemistry, Materials Science, or a related field. A solid background in surface science and previous experience using ultrahigh vacuum surface analysis equipment would be a benefit, is, however, not expected. Excellent communication skills in English are required.
Conditions of employment. The position is available immediately for 3 years. The salary will be according to the German TV-L (66%). The preferred starting date would be Juli 2023 but it can be negotiated.
Application. The application should include your CV, one-page motivation letter, Master/Diploma certificate, transcript of grades, and contact information of 2 references. We expressly encourage women to apply and welcome applications from candidates with disabilities. For further details, see https://www.spm.nat.fau.de or e-mail Prof. Dr. Sabine Maier (sabine.maier@fau.de). The review of applications will begin immediately and continue until the position is filled.
]]>WISSENSCHAFTLICHE MITARBEITERINNEN bzw. WISSENSCHAFTLICHER MITARBEITER (m/w/d)
Vollzeit, auf 36 Monate befristet. Die Vergütung erfolgt nach Entgeltgruppe 13 TV-L
Kenn-Nr.: 10623WE19
IHRE AUFGABEN
IHR PROFIL
Einstellungsvoraussetzung:
Erforderliche Fachkenntnisse und persönliche Fähigkeiten:
UNSER ANGEBOT
Das Institut für Data Engineering an der Technischen Universität Hamburg forscht und lehrt vor allem im Bereich Big Data und Data Engineering. Ein Schwerpunkt liegt dabei auf Themenstellungen im Bereich der verteilten Datenverarbeitung. Das Institut bietet Ihnen:
Haben Sie noch Fragen? Dann wenden Sie sich gerne an Prof. Dr.-Ing. Stefan Schulte (stefan.schulte@tuhh.de).
Die TUHH steht für Chancengleichheit sowie ein wertschätzendes und respektvolles Miteinander.
Wir fordern insbesondere Frauen auf, sich zu bewerben. Sie werden aufgrund ihrer Unterrepräsentanz bei gleicher Eignung, Befähigung und fachlicher Leistung vorrangig berücksichtigt.
Bitte übersenden Sie Ihre vollständigen Bewerbungsunterlagen (Anschreiben, tabellarischer Lebenslauf, Nachweis der abgeschlossenen Ausbildung oder Hochschulabschluss) über das Online-Bewerbersystem https://stellenportal.tuhh.de/pvtap bis zum 10.04.2023.
]]>wissenschaftlichen Mitarbeiterin*wissenschaftlichen Mitarbeiters (m-w-d)
in Teilzeit (50 %) zu besetzen.
Die Vergütung erfolgt je nach Aufgabenübertragung und Erfüllung der persönlichen Voraussetzungen bis
zur Entgeltgruppe 13 TV-L.
Während der Beschäftigung wird die Promotion zum Dr. rer. nat. angestrebt.
Arbeitsaufgaben:
• Herstellung von Perowskit-Dünnschichten durch Verdampfung und Präparation von Solarzellen
• Charakterisierung von Dünnschichten und Solarzellen
• Weiterentwicklung von Präparations- und Charakterisierungsverfahren
• Beteiligung an Lehraufgaben
Voraussetzungen:
• Überdurchschnittlicher wissenschaftlicher Hochschulabschluss (Diplom, Master) in Physik oder vergleichbarer
Abschluss
• Gute Kenntnisse in Halbleiterphysik und Photovoltaik
• möglichst Erfahrungen in der Präparation und Charakterisierung von Dünnschichten und Solarzellen
• möglichst Kenntnisse über thermische Verdampfung und Röntgendiffraktometrie
Bewerbungen von Schwerbehinderten werden bei gleicher Eignung und Befähigung bevorzugt berücksichtigt. Frauen werden nachdrücklich aufgefordert, sich zu bewerben. Bewerber*innen mit einem Abschluss, der nicht an einer deutschen Hochschule erworben wurde, müssen zum Nachweis der Gleichwertigkeit eine Zeugnisbewertung für ausländische Hochschulqualifikationen (Statement of
Comparability for Foreign Higher Education Qualifications) der Zentralstelle für ausländisches Bildungswesen vorlegen.
Bei Rückfragen wenden Sie sich bitte an Herrn Prof. Dr. Scheer, Tel.: 0345 55-25490, E-Mail: roland.scheer@physik.uni-halle.de.
Ihre Bewerbung richten Sie bitte unter Angabe der Reg.-Nr. 5-5712/22-H mit den üblichen Unterlagen bis zum
06.05.2022 an die Martin-Luther-Universität Halle-Wittenberg, Institut für Physik, Prof. Dr. Scheer, roland.
scheer@physik.uni-halle.de.
Die Ausschreibung erfolgt unter Vorbehalt eventueller haushaltsrechtlicher Restriktionen. Bewerbungskosten werden von der Martin-Luther-Universität nicht erstattet. Bewerbungsunterlagen werden nur zurückgesandt, wenn ein ausreichend frankierter Rückumschlag beigefügt wurde. Eine elektronische Bewerbung
ist erwünscht.